ID   RECN_HELPY              Reviewed;         524 AA.
AC   O25943;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=DNA repair protein RecN;
DE   AltName: Full=Recombination protein N;
GN   Name=recN; OrderedLocusNames=HP_1393;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD08433.1; -; Genomic_DNA.
DR   PIR; A64694; A64694.
DR   RefSeq; NP_208184.1; NC_000915.1.
DR   RefSeq; WP_001204425.1; NC_018939.1.
DR   AlphaFoldDB; O25943; -.
DR   SMR; O25943; -.
DR   DIP; DIP-3217N; -.
DR   IntAct; O25943; 5.
DR   MINT; O25943; -.
DR   STRING; 85962.C694_07195; -.
DR   PaxDb; O25943; -.
DR   EnsemblBacteria; AAD08433; AAD08433; HP_1393.
DR   KEGG; hpy:HP_1393; -.
DR   PATRIC; fig|85962.47.peg.1492; -.
DR   eggNOG; COG0497; Bacteria.
DR   OMA; QVICVTH; -.
DR   PhylomeDB; O25943; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR   GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004604; DNA_recomb/repair_RecN.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   PANTHER; PTHR11059; PTHR11059; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF003128; RecN; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..524
FT                   /note="DNA repair protein RecN"
FT                   /id="PRO_0000188019"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   524 AA;  59565 MW;  1F78EBFF0CFCE68A CRC64;
     MRDFNNAQIT RLKVRQNAVF EKLDLEFKDG LSAISGASGV GKSVLIASLL GAFGLKESNA
     SNIEVELIAP FLDTEEYGIF REDEHEPLVI SVIKKEKTRY FLNQTSLSKN TLKALLKGLI
     KRLSNDRFSQ NELNDILMLS LLDGYIQNEN KAFSPLLGAL EEKFTRLEKL EKERRLLEDK
     KRFQKDLEER LNFEKMKLER LDLKEDEYER LLEQKKLLSS KEKLNDKIAL ALEVLENTHK
     ITHALESVGH SAEFLKSALL EASALLEKEQ AKLEECERLD IEKVLERLGM LSGIIKDYGS
     IMHAKERLGH VKNELHNLKE IDSHCETYHK EIERLKTECL KLCEEISGFR KEYLAGFNAL
     LSAKAKDLLL KSPSLVLEDA PMSEKGAQKL VLNLQNSQLE TLSSGEYSRL RLAFMLLEME
     FLKDFKGVLV LDEMDSNLSG EESLAVSKAL ETLSSHSQIF AISHQVHIPA LAKNHILVFK
     ENHKSLAKTL NNEERVLEIA RMIGGSENIE SAISFAKEKL KAQE