RECN_MYCBO
ID RECN_MYCBO Reviewed; 587 AA.
AC P0A5U7; A0A1R3XZE7; O33197; X2BIP1;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=DNA repair protein RecN;
DE AltName: Full=Recombination protein N;
GN Name=recN; OrderedLocusNames=BQ2027_MB1722;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
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DR EMBL; LT708304; SIU00326.1; -; Genomic_DNA.
DR RefSeq; NP_855375.1; NC_002945.3.
DR RefSeq; WP_003408385.1; NC_002945.4.
DR AlphaFoldDB; P0A5U7; -.
DR SMR; P0A5U7; -.
DR EnsemblBacteria; SIU00326; SIU00326; BQ2027_MB1722.
DR GeneID; 45425665; -.
DR PATRIC; fig|233413.5.peg.1878; -.
DR OMA; QVICVTH; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR PANTHER; PTHR11059; PTHR11059; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR TIGRFAMs; TIGR00634; recN; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA damage; DNA repair; Nucleotide-binding.
FT CHAIN 1..587
FT /note="DNA repair protein RecN"
FT /id="PRO_0000188023"
FT BINDING 29..36
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 587 AA; 62229 MW; 4B7051EFB60102E7 CRC64;
MLTELRIESL GAISVATAEF DRGFTVLTGE TGTGKTMVVT GLHLLGGARA DATRVRSGAD
RAVVEGRFTT TDLDDATVAG LQAVLDSSGA ERDEDGSVIA LRSISRDGPS RAYLGGRGVP
AKSLSGFTNE LLTLHGQNDQ LRLMRPDEQR GALDRFAAAG EAVQRYRKLR DAWLTARRDL
VDRRNRAREL AQEADRLKFA LNEIDTVDPQ PGEDVALVAD IARLSELDTL REAATTARAT
LCGTPDADAF DRGAVDSLGR ARAALQSSDD AALRGLAEQV GEALTVVVDA VAELGAYLDE
LPADASALDA KLARQAQLRT LTRKYAADID GVLRWADEAR ARLAQLDVSE EGLAALERRT
GELAHELGQA AVDLSTIRRK AAKRLAKEVS AELSALAMAD AEFTIGVTTE LADHGDPVAL
ALASGELARA GADGVDAVEF GFVAHRGMTV LPLAKSASGG ELSRVMLSLE VVLATSRKQA
AGTTMVFDEI DAGVGGWAAV QIGRRLARLA RTHQVIVVTH LPQVAAYADV HLMVQRTGRD
GASGVRRLTS EDRVAELARM LAGLGDSDSG RAHARELLET AQNDELT