位置:首页 > 蛋白库 > RECN_MYCLE
RECN_MYCLE
ID   RECN_MYCLE              Reviewed;         587 AA.
AC   Q49896; O08103;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=DNA repair protein RecN;
DE   AltName: Full=Recombination protein N;
GN   Name=recN; OrderedLocusNames=ML1360; ORFNames=MLC1351.12c;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00021; AAA50914.1; -; Genomic_DNA.
DR   EMBL; Z95117; CAB08275.1; -; Genomic_DNA.
DR   EMBL; AL583921; CAC31741.1; -; Genomic_DNA.
DR   PIR; S72966; S72966.
DR   RefSeq; NP_301970.1; NC_002677.1.
DR   RefSeq; WP_010908291.1; NC_002677.1.
DR   AlphaFoldDB; Q49896; -.
DR   SMR; Q49896; -.
DR   STRING; 272631.ML1360; -.
DR   EnsemblBacteria; CAC31741; CAC31741; CAC31741.
DR   KEGG; mle:ML1360; -.
DR   PATRIC; fig|272631.5.peg.2517; -.
DR   Leproma; ML1360; -.
DR   eggNOG; COG0497; Bacteria.
DR   HOGENOM; CLU_018297_3_0_11; -.
DR   OMA; QVICVTH; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR004604; DNA_recomb/repair_RecN.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   PANTHER; PTHR11059; PTHR11059; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF003128; RecN; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR00634; recN; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..587
FT                   /note="DNA repair protein RecN"
FT                   /id="PRO_0000188021"
FT   BINDING         29..36
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   587 AA;  62724 MW;  58BC63F38A4DB732 CRC64;
     MLTEIRIESL GAISVATAEF DRGLTVLTGE TGTGKTMVVT GLHLLGGARA DASRVRSGAN
     RAVVEGRFTT TDLDDVVVAQ LDGILNASGS ERDEDGSVIV LRSVSRDGPS RSYLGGRSVP
     AKSLGSFTTE LLALHGQNDQ LRLVRPEEQR AALDRYAAAG PSCERYRELR DAWLLARSDL
     IDRRNRIREL VQEADRLKFA LSEIDSVDPQ PGEDNALVAD IVRLSELDML REVAVNARAA
     LSGALDDMDV SGSNAVACMG QAKAALESTD DATLRAFADQ VGEVLTVVVE VGRELGEYLE
     ELPVDASALE SKLVRQAELC TLTRKYAADI DGVLQWARES RERLEQLDVS YERLAGVESR
     VDELERQLSQ AAVDLSKLRR DAANRLAKEV TAELSALAMV DAEFTISVTT DLIPLTDYKR
     SAAVTLPSGG VARAGADGVD QVEFGFAAHR GMTVLPLAKS ASGGELSRVM LALEVVLATS
     AAGTTMVFDE VDVGVGGRAA VQIGRRLARL ARTHQVIVVT HLPQVAAYAD VHLVVHSAGL
     DGASDVRRLA GDDRVAELAR MLAGLGESDS GRAHARELLD AARKDKS
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024