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RECN_STRCO
ID   RECN_STRCO              Reviewed;         572 AA.
AC   Q9S220;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=DNA repair protein RecN;
DE   AltName: Full=Recombination protein N;
GN   Name=recN; OrderedLocusNames=SCO1780; ORFNames=SCI51.20c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
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DR   EMBL; AL939110; CAB52844.1; -; Genomic_DNA.
DR   PIR; T36883; T36883.
DR   RefSeq; NP_626051.1; NC_003888.3.
DR   RefSeq; WP_011027972.1; NC_003888.3.
DR   AlphaFoldDB; Q9S220; -.
DR   SMR; Q9S220; -.
DR   STRING; 100226.SCO1780; -.
DR   GeneID; 1097211; -.
DR   KEGG; sco:SCO1780; -.
DR   PATRIC; fig|100226.15.peg.1799; -.
DR   eggNOG; COG0497; Bacteria.
DR   HOGENOM; CLU_018297_3_0_11; -.
DR   InParanoid; Q9S220; -.
DR   OMA; QVICVTH; -.
DR   PhylomeDB; Q9S220; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR   GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR004604; DNA_recomb/repair_RecN.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   PANTHER; PTHR11059; PTHR11059; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF003128; RecN; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR00634; recN; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..572
FT                   /note="DNA repair protein RecN"
FT                   /id="PRO_0000188026"
FT   BINDING         25..32
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   572 AA;  59837 MW;  1D303A47D50BBC14 CRC64;
     MRIRSLGVID DAVVELSPGF TAVTGETGAG KTMVVTSLGL LLGGRADAAL VRIGAKNAVV
     EGRIAVPGDA AVAVRAEEAG AELDDGALLI SRTVSAEGRS RAHLGGRSVP VGMLAELADE
     LVAVHGQTDQ QGLLKLNRQR QALDRYAGDA VAGPLAKYAE AYRRLRAVVR ELEEITTRAR
     ERAQEADLLR YGLDEIAAVE PRAGEDVELA EEAERLGHAE ALASAATVAH AALAGNPEDP
     EGVDGATLVA GAQRALDAVR SHDPALAALA ERIGEVGILL RDVAGELAGY ADDLDADPLR
     LAAVEERRAA LTALTRKYGE DIAAVLSWAE QSAARLTELD GDDERIGELT AERDALRAEL
     GGLAQALTDA RTEAAERFAA AVTAELASLA MPHARVSFAI RQTEDPEGVE IGGRTVAYGP
     SGADEVELLL APHPGAPARP IAKGASGGEL SRVMLAVEVV FAGTDPVPTY LFDEVDAGVG
     GKAAVEIGRR LARLARSAQV VVVTHLPQVA AFADRQLLVE KTNDGSVTRS GVKVLEGEER
     VRELSRMLAG QEDSETARAH AEELLETARA DR
 
 
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