RECO_ECOLI
ID RECO_ECOLI Reviewed; 242 AA.
AC P0A7H3; P15027; P76589; Q2MAG5;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=DNA repair protein RecO;
DE AltName: Full=Recombination protein O;
GN Name=recO; OrderedLocusNames=b2565, JW2549;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], DISRUPTION PHENOTYPE, AND OPERON
RP STRUCTURE.
RC STRAIN=K12 / W3110;
RX PubMed=2540151; DOI=10.1128/jb.171.5.2581-2590.1989;
RA Takiff H.E., Chen S.M., Court D.L.;
RT "Genetic analysis of the rnc operon of Escherichia coli.";
RL J. Bacteriol. 171:2581-2590(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2544549; DOI=10.1128/jb.171.7.3641-3649.1989;
RA Morrison P.T., Lovett S.T., Gilson L.E., Kolodner R.;
RT "Molecular analysis of the Escherichia coli recO gene.";
RL J. Bacteriol. 171:3641-3649(1989).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RA Nashimoto H., Saito N.;
RL Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [6]
RP PROTEIN SEQUENCE OF 1-14, AND SUBUNIT.
RX PubMed=8107098; DOI=10.1006/jmbi.1994.1123;
RA Luisi-DeLuca C., Kolodner R.;
RT "Purification and characterization of the Escherichia coli RecO protein.
RT Renaturation of complementary single-stranded DNA molecules catalyzed by
RT the RecO protein.";
RL J. Mol. Biol. 236:124-138(1994).
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 225-242.
RC STRAIN=K12;
RX PubMed=1537800; DOI=10.1128/jb.174.5.1554-1567.1992;
RA Lam H.-M., Tancula E., Dempsey W.B., Winkler M.E.;
RT "Suppression of insertions in the complex pdxJ operon of Escherichia coli
RT K-12 by lon and other mutations.";
RL J. Bacteriol. 174:1554-1567(1992).
CC -!- FUNCTION: Involved in DNA repair and RecF pathway recombination.
CC -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:8107098}.
CC -!- INTERACTION:
CC P0A7H3; P0A7H6: recR; NbExp=3; IntAct=EBI-1129540, EBI-1117436;
CC P0A7H3; P0AGE0: ssb; NbExp=3; IntAct=EBI-1129540, EBI-1118620;
CC -!- INDUCTION: Encoded in the rnc-era-recO operon.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:2540151}.
CC -!- SIMILARITY: Belongs to the RecO family. {ECO:0000305}.
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DR EMBL; M26416; AAA21842.1; -; Genomic_DNA.
DR EMBL; M27251; AAA24515.1; -; Genomic_DNA.
DR EMBL; D64044; BAA10912.1; -; Genomic_DNA.
DR EMBL; M76470; AAA21844.1; -; Genomic_DNA.
DR EMBL; U36841; AAA79827.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75618.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76741.1; -; Genomic_DNA.
DR EMBL; M74526; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; JS0116; BVECRO.
DR RefSeq; NP_417060.1; NC_000913.3.
DR RefSeq; WP_000399404.1; NZ_STEB01000011.1.
DR PDB; 3Q8D; X-ray; 2.30 A; A/B=1-242.
DR PDBsum; 3Q8D; -.
DR AlphaFoldDB; P0A7H3; -.
DR SMR; P0A7H3; -.
DR BioGRID; 4259430; 175.
DR ComplexPortal; CPX-5126; RecOR complex.
DR DIP; DIP-48093N; -.
DR IntAct; P0A7H3; 10.
DR STRING; 511145.b2565; -.
DR PaxDb; P0A7H3; -.
DR PRIDE; P0A7H3; -.
DR EnsemblBacteria; AAC75618; AAC75618; b2565.
DR EnsemblBacteria; BAE76741; BAE76741; BAE76741.
DR GeneID; 947038; -.
DR KEGG; ecj:JW2549; -.
DR KEGG; eco:b2565; -.
DR PATRIC; fig|1411691.4.peg.4169; -.
DR EchoBASE; EB0825; -.
DR eggNOG; COG1381; Bacteria.
DR HOGENOM; CLU_066645_1_0_6; -.
DR InParanoid; P0A7H3; -.
DR OMA; YVLHSRA; -.
DR PhylomeDB; P0A7H3; -.
DR BioCyc; EcoCyc:EG10832-MON; -.
DR BioCyc; MetaCyc:EG10832-MON; -.
DR PRO; PR:P0A7H3; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0043590; C:bacterial nucleoid; IBA:GO_Central.
DR GO; GO:0006310; P:DNA recombination; IDA:ComplexPortal.
DR GO; GO:0006302; P:double-strand break repair; IBA:GO_Central.
DR GO; GO:0009314; P:response to radiation; IMP:EcoCyc.
DR Gene3D; 1.20.1440.120; -; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00201; RecO; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR022572; DNA_rep/recomb_RecO_N.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR003717; RecO.
DR InterPro; IPR042242; RecO_C.
DR PANTHER; PTHR33991; PTHR33991; 1.
DR Pfam; PF02565; RecO_C; 1.
DR Pfam; PF11967; RecO_N; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR SUPFAM; SSF57863; SSF57863; 1.
DR TIGRFAMs; TIGR00613; reco; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; DNA damage; DNA recombination;
KW DNA repair; Reference proteome.
FT CHAIN 1..242
FT /note="DNA repair protein RecO"
FT /id="PRO_0000204949"
FT STRAND 4..14
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 16..18
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 20..26
FT /evidence="ECO:0007829|PDB:3Q8D"
FT TURN 27..29
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 30..36
FT /evidence="ECO:0007829|PDB:3Q8D"
FT TURN 37..40
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 46..49
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 56..61
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 63..75
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 84..99
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 107..121
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 128..142
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 148..150
FT /evidence="ECO:0007829|PDB:3Q8D"
FT TURN 152..154
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 163..167
FT /evidence="ECO:0007829|PDB:3Q8D"
FT TURN 168..170
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 171..174
FT /evidence="ECO:0007829|PDB:3Q8D"
FT STRAND 182..184
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 185..193
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 199..213
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 214..216
FT /evidence="ECO:0007829|PDB:3Q8D"
FT HELIX 223..229
FT /evidence="ECO:0007829|PDB:3Q8D"
SQ SEQUENCE 242 AA; 27391 MW; D21C242C2F842D74 CRC64;
MEGWQRAFVL HSRPWSETSL MLDVFTEESG RVRLVAKGAR SKRSTLKGAL QPFTPLLLRF
GGRGEVKTLR SAEAVSLALP LSGITLYSGL YINELLSRVL EYETRFSELF FDYLHCIQSL
AGVTGTPEPA LRRFELALLG HLGYGVNFTH CAGSGEPVDD TMTYRYREEK GFIASVVIDN
KTFTGRQLKA LNAREFPDAD TLRAAKRFTR MALKPYLGGK PLKSRELFRQ FMPKRTVKTH
YE
