ID   RECO_STRP1              Reviewed;         251 AA.
AC   P65987; Q491T0; Q9A1Z6;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=DNA repair protein RecO;
DE   AltName: Full=Recombination protein O;
GN   Name=recO; OrderedLocusNames=SPy_0021, M5005_Spy0019;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- FUNCTION: Involved in DNA repair and RecF pathway recombination.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecO family. {ECO:0000305}.
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DR   EMBL; AE004092; AAK33160.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ50638.1; -; Genomic_DNA.
DR   RefSeq; NP_268438.1; NC_002737.2.
DR   AlphaFoldDB; P65987; -.
DR   SMR; P65987; -.
DR   STRING; 1314.HKU360_00051; -.
DR   PaxDb; P65987; -.
DR   EnsemblBacteria; AAK33160; AAK33160; SPy_0021.
DR   KEGG; spy:SPy_0021; -.
DR   KEGG; spz:M5005_Spy0019; -.
DR   PATRIC; fig|160490.10.peg.20; -.
DR   HOGENOM; CLU_066632_4_0_9; -.
DR   OMA; CPQHYHE; -.
DR   Proteomes; UP000000750; Chromosome.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1440.120; -; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00201; RecO; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR022572; DNA_rep/recomb_RecO_N.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR003717; RecO.
DR   InterPro; IPR042242; RecO_C.
DR   PANTHER; PTHR33991; PTHR33991; 1.
DR   Pfam; PF02565; RecO_C; 1.
DR   Pfam; PF11967; RecO_N; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF57863; SSF57863; 1.
DR   TIGRFAMs; TIGR00613; reco; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA recombination; DNA repair; Reference proteome.
FT   CHAIN           1..251
FT                   /note="DNA repair protein RecO"
FT                   /id="PRO_0000205011"
SQ   SEQUENCE   251 AA;  29517 MW;  8F619EC731A470E4 CRC64;
     MQLTESLGIV LFNRNYREDD KLVKIFTEVA GKQMFFVKHI SRSKMSSIIQ PLTIADFIFK
     LNDTGLSYVV DYSNVNTYRY INNDIFRLAY ASYVLALADA AIADNESDSH LFTFLKKTLD
     LMEEGLDYEI LTNIFEIQIL DRFGISLNFH ECAICHRTDL PLDFSHRFSA VLCSEHYYKD
     NRRNHLDPNV IYLLSRFQKI TFDDLRTISL NKDIKKKLRQ FIDELYHDYV GIKLKSKTFI
     DNLVKWGDIM K