ID   RECQ_PASMU              Reviewed;         632 AA.
AC   Q9CL21;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=ATP-dependent DNA helicase RecQ;
DE            EC=3.6.4.12;
GN   Name=recQ; OrderedLocusNames=PM1427;
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70;
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- FUNCTION: DNA helicase. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC   -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE004439; AAK03511.1; -; Genomic_DNA.
DR   RefSeq; WP_010907159.1; NC_002663.1.
DR   AlphaFoldDB; Q9CL21; -.
DR   SMR; Q9CL21; -.
DR   STRING; 747.DR93_282; -.
DR   EnsemblBacteria; AAK03511; AAK03511; PM1427.
DR   KEGG; pmu:PM1427; -.
DR   PATRIC; fig|272843.6.peg.1441; -.
DR   HOGENOM; CLU_001103_14_3_6; -.
DR   OMA; HHDIPKS; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.80; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010997; HRDC-like_sf.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR044876; HRDC_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032284; RecQ_Zn-bd.
DR   InterPro; IPR018982; RQC_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   Pfam; PF16124; RecQ_Zn_bind; 1.
DR   Pfam; PF09382; RQC; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SMART; SM00956; RQC; 1.
DR   SUPFAM; SSF47819; SSF47819; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR01389; recQ; 1.
DR   TIGRFAMs; TIGR00614; recQ_fam; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..632
FT                   /note="ATP-dependent DNA helicase RecQ"
FT                   /id="PRO_0000205037"
FT   DOMAIN          47..215
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          236..385
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   DOMAIN          544..624
FT                   /note="HRDC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00328"
FT   MOTIF           159..162
FT                   /note="DEAH box"
FT   BINDING         60..67
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   632 AA;  71645 MW;  B4C94B9BD7CF9D1B CRC64;
     MFSSSLLSKD NKSAVDFHEI PLKQTALDVL HAVFGYQSFR KGQEEVIDAT LMGKDSLVIM
     ATGNGKSLCY QIPALCFEGL TLVISPLISL MKDQVDQLLA NGIEADYLNS SQTFTEQQQV
     QNKLMSGTLK LLYVSPEKVM TTSFFHLISH CKVSFVAIDE AHCISQWGHD FRPEYTQLGG
     LKSCFPHAPI MALTATADHA TRQDILRHLN LQSPHVYIGS FDRPNIRYTL VEKFKPMEQL
     CRFVLGQKGK SGIIYCNSRS KVERIAESLR NKGVSAQAYH AGLETSQREQ VQRAFQRDNV
     QVVVATIAFG MGINKSNVRF VVHFDLPRSI ESYYQETGRA GRDDLPAEAV LFYEPADYAW
     LHKILLEKPE SPQRQIEALK LQAIGEFAES QTCRRLVLLN YFGEHQQKPC QNCDICLDPP
     KQYDGLIDAQ KVMSTIYRIG QRFGVHYVIA VLRGLSNQKI KDNQHEQLSV YGIGKDKSKE
     HWQSVIRQLI HLGFIKQVFD HFNATLQLTE NAKPILRGEQ PLSLAMPRIS SLTSVVAPQR
     YAIAQYDKDL FARLRFLRKQ IADKENIPAY IVFNDATLQE MAQYQPTTKA EMLAINGVGA
     TKFERFAQPF MQIIQQHKKV LTQHEPPLSL ES