RECR_ECOLI
ID RECR_ECOLI Reviewed; 201 AA.
AC P0A7H6; P12727; Q2MBV5;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Recombination protein RecR {ECO:0000255|HAMAP-Rule:MF_00017};
GN Name=recR {ECO:0000255|HAMAP-Rule:MF_00017};
GN OrderedLocusNames=b0472, JW0461;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=1698765; DOI=10.1128/jb.172.10.6042-6047.1990;
RA Yeung T., Mullin D.A., Chen K.S., Craig E.A., Bardwell J.C.A., Walker J.R.;
RT "Sequence and expression of the Escherichia coli recR locus.";
RL J. Bacteriol. 172:6042-6047(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=2674903; DOI=10.1093/nar/17.17.6781;
RA Mahdi A.A., Lloyd R.G.;
RT "The recR locus of Escherichia coli K-12: molecular cloning, DNA sequencing
RT and identification of the gene product.";
RL Nucleic Acids Res. 17:6781-6794(1989).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: May play a role in DNA repair. It seems to be involved in an
CC RecBC-independent recombinational process of DNA repair. It may act
CC with RecF and RecO.
CC -!- INTERACTION:
CC P0A7H6; P0A7H3: recO; NbExp=3; IntAct=EBI-1117436, EBI-1129540;
CC -!- SIMILARITY: Belongs to the RecR family. {ECO:0000255|HAMAP-
CC Rule:MF_00017}.
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DR EMBL; X15761; CAA33768.1; -; Genomic_DNA.
DR EMBL; M38777; AAA23459.1; -; Genomic_DNA.
DR EMBL; U82664; AAB40226.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73574.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76251.1; -; Genomic_DNA.
DR PIR; JU0106; BVECRR.
DR RefSeq; NP_415005.1; NC_000913.3.
DR RefSeq; WP_001195025.1; NZ_STEB01000007.1.
DR AlphaFoldDB; P0A7H6; -.
DR SMR; P0A7H6; -.
DR BioGRID; 4261966; 176.
DR ComplexPortal; CPX-5126; RecOR complex.
DR DIP; DIP-341N; -.
DR IntAct; P0A7H6; 6.
DR STRING; 511145.b0472; -.
DR jPOST; P0A7H6; -.
DR PaxDb; P0A7H6; -.
DR PRIDE; P0A7H6; -.
DR EnsemblBacteria; AAC73574; AAC73574; b0472.
DR EnsemblBacteria; BAE76251; BAE76251; BAE76251.
DR GeneID; 66671226; -.
DR GeneID; 945100; -.
DR KEGG; ecj:JW0461; -.
DR KEGG; eco:b0472; -.
DR PATRIC; fig|1411691.4.peg.1804; -.
DR EchoBASE; EB0827; -.
DR eggNOG; COG0353; Bacteria.
DR HOGENOM; CLU_060739_1_2_6; -.
DR InParanoid; P0A7H6; -.
DR OMA; DVMAIEN; -.
DR PhylomeDB; P0A7H6; -.
DR BioCyc; EcoCyc:EG10834-MON; -.
DR BioCyc; MetaCyc:EG10834-MON; -.
DR PRO; PR:P0A7H6; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IDA:ComplexPortal.
DR GO; GO:0000731; P:DNA synthesis involved in DNA repair; IMP:EcoliWiki.
DR GO; GO:0009314; P:response to radiation; IMP:EcoCyc.
DR GO; GO:0009411; P:response to UV; IMP:EcoliWiki.
DR CDD; cd01025; TOPRIM_recR; 1.
DR HAMAP; MF_00017; RecR; 1.
DR InterPro; IPR000093; DNA_Rcmb_RecR.
DR InterPro; IPR023627; Rcmb_RecR.
DR InterPro; IPR023628; Rcmb_RecR_C4-type_Zn.
DR InterPro; IPR015967; Rcmb_RecR_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR InterPro; IPR034137; TOPRIM_RecR.
DR PANTHER; PTHR30446; PTHR30446; 1.
DR Pfam; PF02132; RecR; 1.
DR Pfam; PF13662; Toprim_4; 1.
DR SMART; SM00493; TOPRIM; 1.
DR SUPFAM; SSF111304; SSF111304; 1.
DR TIGRFAMs; TIGR00615; recR; 1.
DR PROSITE; PS01300; RECR; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 1: Evidence at protein level;
KW DNA damage; DNA recombination; DNA repair; Metal-binding;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..201
FT /note="Recombination protein RecR"
FT /id="PRO_0000190316"
FT DOMAIN 81..176
FT /note="Toprim"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00017"
FT ZN_FING 57..72
FT /note="C4-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00017"
FT CONFLICT 32
FT /note="L -> V (in Ref. 1; AAA23459)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 201 AA; 21963 MW; F527EE1C809E47E9 CRC64;
MQTSPLLTQL MEALRCLPGV GPKSAQRMAF TLLQRDRSGG MRLAQALTRA MSEIGHCADC
RTFTEQEVCN ICSNPRRQEN GQICVVESPA DIYAIEQTGQ FSGRYFVLMG HLSPLDGIGP
DDIGLDRLEQ RLAEEKITEV ILATNPTVEG EATANYIAEL CAQYDVEASR IAHGVPVGGE
LEMVDGTTLS HSLAGRHKIR F
