RECR_MYCLE
ID RECR_MYCLE Reviewed; 203 AA.
AC O69520;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Recombination protein RecR {ECO:0000255|HAMAP-Rule:MF_00017};
GN Name=recR {ECO:0000255|HAMAP-Rule:MF_00017}; OrderedLocusNames=ML2329;
GN ORFNames=MLCB2407.21;
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN;
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- FUNCTION: May play a role in DNA repair. It seems to be involved in an
CC RecBC-independent recombinational process of DNA repair. It may act
CC with RecF and RecO. {ECO:0000255|HAMAP-Rule:MF_00017}.
CC -!- SIMILARITY: Belongs to the RecR family. {ECO:0000255|HAMAP-
CC Rule:MF_00017}.
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DR EMBL; AL023596; CAA19161.1; -; Genomic_DNA.
DR EMBL; AL583925; CAC31845.1; -; Genomic_DNA.
DR PIR; E87200; E87200.
DR RefSeq; NP_302515.1; NC_002677.1.
DR RefSeq; WP_010908835.1; NC_002677.1.
DR AlphaFoldDB; O69520; -.
DR SMR; O69520; -.
DR STRING; 272631.ML2329; -.
DR EnsemblBacteria; CAC31845; CAC31845; CAC31845.
DR KEGG; mle:ML2329; -.
DR PATRIC; fig|272631.5.peg.4458; -.
DR Leproma; ML2329; -.
DR eggNOG; COG0353; Bacteria.
DR HOGENOM; CLU_060739_1_0_11; -.
DR OMA; DVMAIEN; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0140640; F:catalytic activity, acting on a nucleic acid; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR CDD; cd01025; TOPRIM_recR; 1.
DR HAMAP; MF_00017; RecR; 1.
DR InterPro; IPR000093; DNA_Rcmb_RecR.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR023627; Rcmb_RecR.
DR InterPro; IPR023628; Rcmb_RecR_C4-type_Zn.
DR InterPro; IPR015967; Rcmb_RecR_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR InterPro; IPR034137; TOPRIM_RecR.
DR PANTHER; PTHR30446; PTHR30446; 1.
DR Pfam; PF02132; RecR; 1.
DR Pfam; PF13662; Toprim_4; 1.
DR SMART; SM00278; HhH1; 1.
DR SMART; SM00493; TOPRIM; 1.
DR SUPFAM; SSF111304; SSF111304; 1.
DR TIGRFAMs; TIGR00615; recR; 1.
DR PROSITE; PS01300; RECR; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW DNA damage; DNA recombination; DNA repair; Metal-binding;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..203
FT /note="Recombination protein RecR"
FT /id="PRO_0000190348"
FT DOMAIN 79..179
FT /note="Toprim"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00017"
FT ZN_FING 56..71
FT /note="C4-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00017"
SQ SEQUENCE 203 AA; 22317 MW; 1069841E0AEC83BE CRC64;
MFEGPVQNLI DELGKLPGIG PKSAQRIAFH LLSVEPQDID RLTAVLVKVR DDVRFCTVCG
NVSDDERCRI CSDTRRDASV VCVVEEPKDV QAVERTREFR GRYHVLGGAL DPLSGIGPEQ
LRIRELLSRI GERVDDVGIT EVIIATDPNT EGEATATYLV RMLRDMPGLT VTRIASGLPM
GGDLEFADEL TLGRALTGRR TMV
