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RECX_ECOL6
ID   RECX_ECOL6              Reviewed;         166 AA.
AC   P65999; P59208; Q8X875;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Regulatory protein RecX;
GN   Name=recX; OrderedLocusNames=c3252;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Modulates RecA activity through direct physical interaction.
CC       Can inhibit both RecA recombinase and coprotease activities. May have a
CC       regulatory role during the SOS response. Inhibits DNA strand exchange
CC       in vitro (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RecX family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN81703.1; -; Genomic_DNA.
DR   RefSeq; WP_000140506.1; NC_004431.1.
DR   AlphaFoldDB; P65999; -.
DR   SMR; P65999; -.
DR   STRING; 199310.c3252; -.
DR   EnsemblBacteria; AAN81703; AAN81703; c3252.
DR   GeneID; 66673433; -.
DR   KEGG; ecc:c3252; -.
DR   eggNOG; COG2137; Bacteria.
DR   HOGENOM; CLU_066607_3_2_6; -.
DR   OMA; RCKMQEK; -.
DR   BioCyc; ECOL199310:C3252-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006282; P:regulation of DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 3.
DR   HAMAP; MF_01114; RecX; 1.
DR   InterPro; IPR003783; Regulatory_RecX.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33602; PTHR33602; 1.
DR   Pfam; PF02631; RecX; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA repair; SOS response.
FT   CHAIN           1..166
FT                   /note="Regulatory protein RecX"
FT                   /id="PRO_0000162430"
SQ   SEQUENCE   166 AA;  19410 MW;  E22E4AED81712E63 CRC64;
     MTESTSRRPA YARLLDRAVR ILAVRDHSEQ ELRRKLAAPI MGKNGPEEID ATAEDYERVI
     AWCHEHGYLD DSRFVARFIA SRSRKGYGPA RIRQELNQKG ISREATEKAM RECDIDWCAL
     ARDQATRKYG EPLPTVFSEK VKIQRFLLYR GYLMEDIQDI WRNFAD
 
 
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