ID   RECX_MYCBO              Reviewed;         174 AA.
AC   P0A5U9; A0A1R3Y206; O33280; X2BLD9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Regulatory protein RecX;
GN   Name=recX; OrderedLocusNames=BQ2027_MB2755C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Binds to RecA inhibiting ATP hydrolysis and the generation of
CC       heteroduplex DNA. It might act as an anti-recombinase to quell
CC       inappropriate recombinational repair during normal DNA metabolism. It
CC       is essential for cell survival (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RecX family. {ECO:0000305}.
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DR   EMBL; LT708304; SIU01373.1; -; Genomic_DNA.
DR   RefSeq; NP_856401.1; NC_002945.3.
DR   RefSeq; WP_003900562.1; NC_002945.4.
DR   AlphaFoldDB; P0A5U9; -.
DR   SMR; P0A5U9; -.
DR   EnsemblBacteria; SIU01373; SIU01373; BQ2027_MB2755C.
DR   PATRIC; fig|233413.5.peg.3018; -.
DR   OMA; WVHSRHT; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006282; P:regulation of DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_01114; RecX; 1.
DR   InterPro; IPR003783; Regulatory_RecX.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33602; PTHR33602; 1.
DR   Pfam; PF02631; RecX; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..174
FT                   /note="Regulatory protein RecX"
FT                   /id="PRO_0000162451"
SQ   SEQUENCE   174 AA;  19146 MW;  029D7FA766488328 CRC64;
     MTVSCPPPST SEREEQARAL CLRLLTARSR TRAELAGQLA KRGYPEDIGN RVLDRLAAVG
     LVDDTDFAEQ WVQSRRANAA KSKRALAAEL HAKGVDDDVI TTVLGGIDAG AERGRAEKLV
     RARLRREVLI DDGTDEARVS RRLVAMLARR GYGQTLACEV VIAELAAERE RRRV