ID   RECX_STRP1              Reviewed;         258 AA.
AC   Q99YP2; Q48XI7;
DT   17-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Regulatory protein RecX;
GN   Name=recX; OrderedLocusNames=SPy_1607, M5005_Spy1320;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- FUNCTION: Modulates RecA activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RecX family. {ECO:0000305}.
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DR   EMBL; AE004092; AAK34384.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ51938.1; -; Genomic_DNA.
DR   RefSeq; NP_269663.1; NC_002737.2.
DR   AlphaFoldDB; Q99YP2; -.
DR   SMR; Q99YP2; -.
DR   STRING; 1314.HKU360_01359; -.
DR   PaxDb; Q99YP2; -.
DR   EnsemblBacteria; AAK34384; AAK34384; SPy_1607.
DR   KEGG; spy:SPy_1607; -.
DR   KEGG; spz:M5005_Spy1320; -.
DR   PATRIC; fig|160490.10.peg.1401; -.
DR   HOGENOM; CLU_066607_4_0_9; -.
DR   OMA; MNYLSYQ; -.
DR   Proteomes; UP000000750; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006282; P:regulation of DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 4.
DR   HAMAP; MF_01114; RecX; 1.
DR   InterPro; IPR003783; Regulatory_RecX.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33602; PTHR33602; 1.
DR   Pfam; PF02631; RecX; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..258
FT                   /note="Regulatory protein RecX"
FT                   /id="PRO_0000162483"
SQ   SEQUENCE   258 AA;  30562 MW;  C15506CD9C1648F7 CRC64;
     MKITKIEKKK RLYLIELDND ESLYVTEDTI VRFMLSKDKV LDNDQLEDMK HFAQLSYGKN
     LALYFLSFQQ RSNKQVADYL RKHEIEEHII ADIITQLQEE QWIDDTKLAD TYIRQNQLNG
     DKGPQVLKQK LLQKGIASHD IDPILSQTDF SQLAQKVSQK LFDKYQEKLP PKALKDKITQ
     ALLTKGFSYD LAKHSLNHLN FDQDNQEIED LLDKELDKQY RKLSRKYDGY TLKQKLYQAL
     YRKGYNSDDI NCKLRNYL