RECX_YERPE
ID RECX_YERPE Reviewed; 187 AA.
AC P37867; Q0WBY6;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2001, sequence version 2.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=Regulatory protein RecX;
GN Name=recX; OrderedLocusNames=YPO3306, y0882, YP_0380;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26.
RC STRAIN=231;
RA Kryukov V.M., Suchkov I.Y., Sazykin I.S., Mishankin B.N.;
RL Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RX PubMed=8165147; DOI=10.1093/nar/22.7.1313;
RA de Mot R., Schoofs G., Vanderleyden J.;
RT "A putative regulatory gene downstream of recA is conserved in Gram-
RT negative and Gram-positive bacteria.";
RL Nucleic Acids Res. 22:1313-1314(1994).
CC -!- FUNCTION: Modulates RecA activity. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RecX family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL590842; CAL21897.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM84466.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS60653.1; -; Genomic_DNA.
DR EMBL; X75336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; AF0401; AF0401.
DR RefSeq; WP_002209447.1; NZ_WUCK01000052.1.
DR RefSeq; YP_002348202.1; NC_003143.1.
DR AlphaFoldDB; P37867; -.
DR SMR; P37867; -.
DR IntAct; P37867; 1.
DR STRING; 214092.YPO3306; -.
DR PaxDb; P37867; -.
DR DNASU; 1145829; -.
DR EnsemblBacteria; AAM84466; AAM84466; y0882.
DR EnsemblBacteria; AAS60653; AAS60653; YP_0380.
DR GeneID; 57975403; -.
DR KEGG; ype:YPO3306; -.
DR KEGG; ypk:y0882; -.
DR KEGG; ypm:YP_0380; -.
DR PATRIC; fig|214092.21.peg.3776; -.
DR eggNOG; COG2137; Bacteria.
DR HOGENOM; CLU_066607_3_2_6; -.
DR OMA; RCKMQEK; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006282; P:regulation of DNA repair; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; -; 3.
DR HAMAP; MF_01114; RecX; 1.
DR InterPro; IPR003783; Regulatory_RecX.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR33602; PTHR33602; 1.
DR Pfam; PF02631; RecX; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..187
FT /note="Regulatory protein RecX"
FT /id="PRO_0000162499"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 17
FT /note="H -> Q (in Ref. 4)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 187 AA; 21631 MW; FBF9FB05C278627C CRC64;
MNDQLSRAMR LLSQRDHSES ELRRKLAAPP FSAKGNWGKR SGAKSSDVVE SNLVESNPVE
SNLAESNAIE ESDPQVIEQV IDYCYQHNWL DDSRFAASYI NSRSRKGYGV QRIRSELMQK
GVDKERILAA FENSEIDWCQ LAKEVAQRKF SETLPVEWKE KAKVQRYLLY RGFFQEEIQS
IYTDSVE