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RECX_YERPE
ID   RECX_YERPE              Reviewed;         187 AA.
AC   P37867; Q0WBY6;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2001, sequence version 2.
DT   25-MAY-2022, entry version 130.
DE   RecName: Full=Regulatory protein RecX;
GN   Name=recX; OrderedLocusNames=YPO3306, y0882, YP_0380;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26.
RC   STRAIN=231;
RA   Kryukov V.M., Suchkov I.Y., Sazykin I.S., Mishankin B.N.;
RL   Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   IDENTIFICATION.
RX   PubMed=8165147; DOI=10.1093/nar/22.7.1313;
RA   de Mot R., Schoofs G., Vanderleyden J.;
RT   "A putative regulatory gene downstream of recA is conserved in Gram-
RT   negative and Gram-positive bacteria.";
RL   Nucleic Acids Res. 22:1313-1314(1994).
CC   -!- FUNCTION: Modulates RecA activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RecX family. {ECO:0000305}.
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DR   EMBL; AL590842; CAL21897.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM84466.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS60653.1; -; Genomic_DNA.
DR   EMBL; X75336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; AF0401; AF0401.
DR   RefSeq; WP_002209447.1; NZ_WUCK01000052.1.
DR   RefSeq; YP_002348202.1; NC_003143.1.
DR   AlphaFoldDB; P37867; -.
DR   SMR; P37867; -.
DR   IntAct; P37867; 1.
DR   STRING; 214092.YPO3306; -.
DR   PaxDb; P37867; -.
DR   DNASU; 1145829; -.
DR   EnsemblBacteria; AAM84466; AAM84466; y0882.
DR   EnsemblBacteria; AAS60653; AAS60653; YP_0380.
DR   GeneID; 57975403; -.
DR   KEGG; ype:YPO3306; -.
DR   KEGG; ypk:y0882; -.
DR   KEGG; ypm:YP_0380; -.
DR   PATRIC; fig|214092.21.peg.3776; -.
DR   eggNOG; COG2137; Bacteria.
DR   HOGENOM; CLU_066607_3_2_6; -.
DR   OMA; RCKMQEK; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006282; P:regulation of DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 3.
DR   HAMAP; MF_01114; RecX; 1.
DR   InterPro; IPR003783; Regulatory_RecX.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33602; PTHR33602; 1.
DR   Pfam; PF02631; RecX; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..187
FT                   /note="Regulatory protein RecX"
FT                   /id="PRO_0000162499"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        17
FT                   /note="H -> Q (in Ref. 4)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   187 AA;  21631 MW;  FBF9FB05C278627C CRC64;
     MNDQLSRAMR LLSQRDHSES ELRRKLAAPP FSAKGNWGKR SGAKSSDVVE SNLVESNPVE
     SNLAESNAIE ESDPQVIEQV IDYCYQHNWL DDSRFAASYI NSRSRKGYGV QRIRSELMQK
     GVDKERILAA FENSEIDWCQ LAKEVAQRKF SETLPVEWKE KAKVQRYLLY RGFFQEEIQS
     IYTDSVE
 
 
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