ID   REG1_PYRHO              Reviewed;         155 AA.
AC   O57818;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator PH0045;
GN   OrderedLocusNames=PH0045;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
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DR   EMBL; BA000001; BAA29113.1; -; Genomic_DNA.
DR   PIR; B71223; B71223.
DR   RefSeq; WP_010884162.1; NC_000961.1.
DR   AlphaFoldDB; O57818; -.
DR   SMR; O57818; -.
DR   STRING; 70601.3256430; -.
DR   EnsemblBacteria; BAA29113; BAA29113; BAA29113.
DR   GeneID; 1443944; -.
DR   KEGG; pho:PH0045; -.
DR   eggNOG; arCOG01580; Archaea.
DR   OMA; FQILIRA; -.
DR   OrthoDB; 97695at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   Pfam; PF13404; HTH_AsnC-type; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS00519; HTH_ASNC_1; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..155
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   PH0045"
FT                   /id="PRO_0000111756"
FT   DOMAIN          4..65
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   155 AA;  17644 MW;  38E8166EFBB5DD4E CRC64;
     MAGIDEIDEV IVRELRKNSR ITLTELGRKV GLTASAVKNR IEKLEKLGVI KGYSAVVDPS
     FFGEFLTAVI EIELIDPDSP DLPRILTPIL KMRNISDVYK KTGEFHLVIR GTFRDVESLN
     TFLKDLKRNY LRNLARRTRI SIVLENFKEA GVTLK