ID   REG2_PYRFU              Reviewed;         148 AA.
AC   Q8TZE2;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator PF2053;
GN   OrderedLocusNames=PF2053;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
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DR   EMBL; AE009950; AAL82177.1; -; Genomic_DNA.
DR   RefSeq; WP_011013199.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8TZE2; -.
DR   SMR; Q8TZE2; -.
DR   STRING; 186497.PF2053; -.
DR   EnsemblBacteria; AAL82177; AAL82177; PF2053.
DR   GeneID; 41713877; -.
DR   KEGG; pfu:PF2053; -.
DR   PATRIC; fig|186497.12.peg.2132; -.
DR   eggNOG; arCOG01581; Archaea.
DR   HOGENOM; CLU_091233_5_4_2; -.
DR   OMA; HIVGPKD; -.
DR   OrthoDB; 97695at2157; -.
DR   PhylomeDB; Q8TZE2; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..148
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   PF2053"
FT                   /id="PRO_0000111758"
FT   DOMAIN          4..65
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   148 AA;  17215 MW;  B6FF32D944E21DE9 CRC64;
     MRRMDKVDLQ LIKILSQNSR LTYRELAEML GTTRQRVARK VDKLKKLGII RKFTIIPNLE
     KLNYMYAILL IKVKATENIY QVAKVLKDHE DVKILELGVG KYNIIAHVLV PKDIKKAQEK
     VNDVIKEING IEDLEVEFVS DIPKFELL