REG4_PYRFU
ID REG4_PYRFU Reviewed; 162 AA.
AC Q8U2H1;
DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator PF0864;
GN OrderedLocusNames=PF0864;
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
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DR EMBL; AE009950; AAL80988.1; -; Genomic_DNA.
DR RefSeq; WP_011011997.1; NZ_CP023154.1.
DR PDB; 2IA0; X-ray; 2.37 A; A/B=2-162.
DR PDBsum; 2IA0; -.
DR AlphaFoldDB; Q8U2H1; -.
DR SMR; Q8U2H1; -.
DR STRING; 186497.PF0864; -.
DR PRIDE; Q8U2H1; -.
DR EnsemblBacteria; AAL80988; AAL80988; PF0864.
DR GeneID; 41712674; -.
DR KEGG; pfu:PF0864; -.
DR PATRIC; fig|186497.12.peg.915; -.
DR eggNOG; arCOG01585; Archaea.
DR HOGENOM; CLU_091233_5_4_2; -.
DR OMA; HFRIKKL; -.
DR OrthoDB; 97695at2157; -.
DR PhylomeDB; Q8U2H1; -.
DR EvolutionaryTrace; Q8U2H1; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PRINTS; PR00033; HTHASNC.
DR SMART; SM00344; HTH_ASNC; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50956; HTH_ASNC_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..162
FT /note="Uncharacterized HTH-type transcriptional regulator
FT PF0864"
FT /id="PRO_0000111764"
FT DOMAIN 6..78
FT /note="HTH asnC-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT DNA_BIND 25..44
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT HELIX 8..19
FT /evidence="ECO:0007829|PDB:2IA0"
FT HELIX 25..32
FT /evidence="ECO:0007829|PDB:2IA0"
FT HELIX 36..48
FT /evidence="ECO:0007829|PDB:2IA0"
FT STRAND 51..59
FT /evidence="ECO:0007829|PDB:2IA0"
FT TURN 61..63
FT /evidence="ECO:0007829|PDB:2IA0"
FT STRAND 66..76
FT /evidence="ECO:0007829|PDB:2IA0"
FT HELIX 82..96
FT /evidence="ECO:0007829|PDB:2IA0"
FT STRAND 101..107
FT /evidence="ECO:0007829|PDB:2IA0"
FT TURN 108..110
FT /evidence="ECO:0007829|PDB:2IA0"
FT STRAND 111..120
FT /evidence="ECO:0007829|PDB:2IA0"
FT HELIX 123..131
FT /evidence="ECO:0007829|PDB:2IA0"
FT TURN 132..134
FT /evidence="ECO:0007829|PDB:2IA0"
FT STRAND 138..145
FT /evidence="ECO:0007829|PDB:2IA0"
FT STRAND 148..151
FT /evidence="ECO:0007829|PDB:2IA0"
FT HELIX 155..159
FT /evidence="ECO:0007829|PDB:2IA0"
SQ SEQUENCE 162 AA; 18457 MW; 171B695E45AFF4A7 CRC64;
MSEIHLDDLD RNILRLLKKD ARLTISELSE QLKKPESTIH FRIKKLQERG VIERYTIILG
EQLKPKHLAL IVLEVGKPVI EDFLERYISY ISSTLSALPG VLFVAKSGED KIIALVGKNN
KDELVKFIEE NITSIPNLKH IQIFPITEIK KGEDLTGFLA EV
