REGA_CERS4
ID REGA_CERS4 Reviewed; 184 AA.
AC Q53228; Q3J6C3; Q53227;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2001, sequence version 2.
DT 25-MAY-2022, entry version 144.
DE RecName: Full=Photosynthetic apparatus regulatory protein RegA;
DE AltName: Full=Response regulator PrrA;
GN Name=regA; Synonyms=prrA; OrderedLocusNames=RHOS4_00930; ORFNames=RSP_1518;
OS Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS sphaeroides).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Cereibacter.
OX NCBI_TaxID=272943;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8181698; DOI=10.1111/j.1574-6968.1994.tb06714.x;
RA Phillips-Jones M.K., Hunter C.N.;
RT "Cloning and nucleotide sequence of regA, a putative response regulator
RT gene of Rhodobacter sphaeroides.";
RL FEMS Microbiol. Lett. 116:269-275(1994).
RN [2]
RP SEQUENCE REVISION TO 98; 180-181 AND 183.
RA Phillips-Jones M.K.;
RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8282708; DOI=10.1128/jb.176.1.32-43.1994;
RA Eraso J.M., Kaplan S.;
RT "prrA, a putative response regulator involved in oxygen regulation of
RT photosynthesis gene expression in Rhodobacter sphaeroides.";
RL J. Bacteriol. 176:32-43(1994).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC / NCIMB 8253 / ATH 2.4.1.;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Member of the two-component regulatory system RegB/RegA.
CC Involved in transactivating anaerobic expression of the photosynthetic
CC apparatus. It is a transcriptional regulator that is responsible for
CC activating expression of the puf, puh, and puc operons in response to a
CC decrease in oxygen tension.
CC -!- PTM: Phosphorylated by RegB. {ECO:0000305}.
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DR EMBL; X76559; CAA54059.2; -; Genomic_DNA.
DR EMBL; L25895; AAA16649.1; -; Unassigned_DNA.
DR EMBL; CP000143; ABA77661.1; -; Genomic_DNA.
DR PIR; A36862; A36862.
DR PIR; S41451; S41451.
DR RefSeq; WP_002722225.1; NZ_CP030271.1.
DR RefSeq; YP_351562.1; NC_007493.2.
DR PDB; 1UMQ; NMR; -; A=125-184.
DR PDBsum; 1UMQ; -.
DR AlphaFoldDB; Q53228; -.
DR BMRB; Q53228; -.
DR SMR; Q53228; -.
DR IntAct; Q53228; 2.
DR MINT; Q53228; -.
DR STRING; 272943.RSP_1518; -.
DR EnsemblBacteria; ABA77661; ABA77661; RSP_1518.
DR GeneID; 57468865; -.
DR GeneID; 67448283; -.
DR KEGG; rsp:RSP_1518; -.
DR PATRIC; fig|272943.9.peg.391; -.
DR eggNOG; COG4567; Bacteria.
DR OMA; RRLEWEH; -.
DR PhylomeDB; Q53228; -.
DR EvolutionaryTrace; Q53228; -.
DR Proteomes; UP000002703; Chromosome 1.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Activator; DNA-binding; Phosphoprotein; Reference proteome;
KW Transcription; Transcription regulation; Two-component regulatory system.
FT CHAIN 1..184
FT /note="Photosynthetic apparatus regulatory protein RegA"
FT /id="PRO_0000081216"
FT DOMAIN 14..128
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT STRAND 137..139
FT /evidence="ECO:0007829|PDB:1UMQ"
FT HELIX 141..155
FT /evidence="ECO:0007829|PDB:1UMQ"
FT HELIX 160..167
FT /evidence="ECO:0007829|PDB:1UMQ"
FT HELIX 171..179
FT /evidence="ECO:0007829|PDB:1UMQ"
SQ SEQUENCE 184 AA; 20484 MW; D73447E037F1285B CRC64;
MAEDLVFELG ADRSLLLVDD DEPFLKRLAK AMEKRGFVLE TAQSVAEGKA IAQARPPAYA
VVDLRLEDGN GLDVVEVLRE RRPDCRIVVL TGYGAIATAV AAVKIGATDY LSKPADANEV
THALLAKGES LPPPPENPMS ADRVRWEHIQ RIYEMCDRNV SETARRLNMH RRTLQRILAK
RSPR
