REGQ_BP82
ID REGQ_BP82 Reviewed; 229 AA.
AC P13870;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=Antitermination protein Q;
GN Name=Q;
OS Enterobacteria phage 82 (Bacteriophage 82).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
OX NCBI_TaxID=10705;
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3624233; DOI=10.1016/s0021-9258(18)60870-1;
RA Goliger J.A., Roberts J.W.;
RT "Bacteriophage 82 gene Q and Q protein. Sequence, overproduction, and
RT activity as a transcription antiterminator in vitro.";
RL J. Biol. Chem. 262:11721-11725(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8648624; DOI=10.1006/jmbi.1996.0185;
RA Mahdi A.A., Sharples G.J., Mandal T.N., Lloyd R.G.;
RT "Holliday junction resolvases encoded by homologous rusA genes in
RT Escherichia coli K-12 and phage 82.";
RL J. Mol. Biol. 257:561-573(1996).
CC -!- FUNCTION: Positively regulates expression of the phage late gene
CC operons. Bacterial host RNA polymerase modified by antitermination
CC proteins transcribes through termination sites that otherwise prevent
CC expression of the regulated genes.
CC -!- SIMILARITY: Belongs to the phage antitermination Q type 1 family.
CC {ECO:0000305}.
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DR EMBL; J02803; AAA32298.1; -; Genomic_DNA.
DR EMBL; X92588; CAA63332.1; -; Genomic_DNA.
DR PIR; A29791; PQBP82.
DR SMR; P13870; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR InterPro; IPR010455; Phage_82_GpQ.
DR Pfam; PF06323; Phage_antiter_Q; 1.
DR PIRSF; PIRSF004417; Anti_term_Q; 1.
PE 3: Inferred from homology;
KW DNA-binding; Transcription; Transcription regulation;
KW Transcription termination.
FT CHAIN 1..229
FT /note="Antitermination protein Q"
FT /id="PRO_0000073886"
FT DNA_BIND 14..32
FT /evidence="ECO:0000255"
SQ SEQUENCE 229 AA; 26400 MW; E6BDABE818498667 CRC64;
MNTQYLQYVR EQLIVATADL SGATKGQLEA WLEHAQFDTG TYKRKKPRIL DEVTGRMITL
DNPPISGKQS YAKGSSIALV SQVEFSTSSW RRAVLSLEEH QKAWLLWSYS ESVRWEHQVT
ITQWAWSEFK TLLGTRKIAG KTLERLKKLI WLAAQDVKNE LAGRKTYEYQ ELASLVGVTS
KNWSETFTER WVAMKHIFLQ LDSEALLLLT RTRSKQKATF SQQNIAKLD