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REGQ_BP933
ID   REGQ_BP933              Reviewed;         144 AA.
AC   P68922; Q9T0Q4; Q9ZWW9;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   02-DEC-2020, entry version 52.
DE   RecName: Full=Antitermination protein Q;
GN   Name=Q; OrderedLocusNames=L0099;
OS   Escherichia phage 933W (Bacteriophage 933W).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Podoviridae; Sepvirinae; Traversvirus.
OX   NCBI_TaxID=10730;
OH   NCBI_TaxID=83334; Escherichia coli O157:H7.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10628842; DOI=10.1007/s004380051122;
RA   Karch H., Schmidt H., Janetzki-Mittmann C., Scheef J., Kroeger M.;
RT   "Shiga toxins even when different are encoded at identical positions in the
RT   genomes of related temperate bacteriophages.";
RL   Mol. Gen. Genet. 262:600-607(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10074068; DOI=10.1128/jb.181.6.1767-1778.1999;
RA   Plunkett G. III, Rose D.J., Durfee T.J., Blattner F.R.;
RT   "Sequence of Shiga toxin 2 phage 933W from Escherichia coli O157:H7: Shiga
RT   toxin as a phage late-gene product.";
RL   J. Bacteriol. 181:1767-1778(1999).
CC   -!- FUNCTION: Positively regulates expression of some phage genes.
CC       Bacterial host RNA polymerase modified by antitermination proteins
CC       transcribes through termination sites that otherwise prevent expression
CC       of the regulated genes (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phage antitermination Q type 1 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD25444.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; Y10775; CAB39299.1; -; Genomic_DNA.
DR   EMBL; AF125520; AAD25444.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_049499.1; NC_000924.1.
DR   SMR; P68922; -.
DR   GeneID; 1261979; -.
DR   KEGG; vg:1261979; -.
DR   Proteomes; UP000002135; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR   GO; GO:0060567; P:negative regulation of DNA-templated transcription, termination; IEA:InterPro.
DR   InterPro; IPR010534; Phage_933W_GpQ.
DR   Pfam; PF06530; Phage_antitermQ; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation;
KW   Transcription termination.
FT   CHAIN           1..144
FT                   /note="Antitermination protein Q"
FT                   /id="PRO_0000073887"
FT   CONFLICT        126
FT                   /note="E -> G (in Ref. 1; CAB39299)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   144 AA;  16532 MW;  5031BE95F3E1BCDC CRC64;
     MRDIRQVLER WGAWAANNYE DVTWSPIAAG FKGLIPEKVK SRPQCCDDDA MVICGCIARL
     YRNNRDLHDL LVDYYVLGET FMALARKHGC SDTCIGKRLH KAEGIVEGML MMLGVRLEMD
     RYVERELPGG RTSVFYQRKN SLRS
 
 
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