REIL2_ARATH
ID REIL2_ARATH Reviewed; 395 AA.
AC Q9ZQ18;
DT 17-FEB-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 164.
DE RecName: Full=Cytoplasmic 60S subunit biogenesis factor REI1 homolog 2 {ECO:0000305};
DE AltName: Full=Protein REI1-LIKE 2 {ECO:0000303|PubMed:24038679};
DE AltName: Full=pre-60S factor REI1 homolog 2 {ECO:0000305};
GN Name=REIL2 {ECO:0000303|PubMed:24038679}; Synonyms=FZF {ECO:0000303|Ref.1};
GN OrderedLocusNames=At2g24500 {ECO:0000312|Araport:AT2G24500};
GN ORFNames=T28I24.23 {ECO:0000312|EMBL:AAD18121.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Jensen R.B., Skriver K., Jespersen H.M.;
RT "FZF, a putative, multiple C2H2 zinc finger protein from Arabidopsis
RT thaliana.";
RL Plant Mol. Biol. 39:637-637(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, INDUCTION BY COLD, AND DISRUPTION PHENOTYPE.
RX PubMed=24038679; DOI=10.1104/pp.113.223925;
RA Schmidt S., Dethloff F., Beine-Golovchuk O., Kopka J.;
RT "The REIL1 and REIL2 proteins of Arabidopsis thaliana are required for leaf
RT growth in the cold.";
RL Plant Physiol. 163:1623-1639(2013).
RN [6]
RP SUBUNIT, AND INTERACTION WITH RLP24; RLP24A; RPL24B; EBP1 AND JJJ1.
RX PubMed=24603461; DOI=10.4161/psb.28224;
RA Schmidt S., Dethloff F., Beine-Golovchuk O., Kopka J.;
RT "REIL proteins of Arabidopsis thaliana interact in yeast-2-hybrid assays
RT with homologs of the yeast Rlp24, Rpl24A, Rlp24B, Arx1, and Jjj1
RT proteins.";
RL Plant Signal. Behav. 9:E28224-E28224(2014).
CC -!- FUNCTION: Pre-60S-associated factor involved in the cytoplasmic
CC maturation of the 60S subunit. Involved in the dissociation and
CC recycling of other late pre-60S factors before newly synthesized large
CC ribosomal subunits enter translation (By similarity). Can complement
CC the growth defect of a yeast mutant lacking REI1 (PubMed:24038679).
CC Required for leaf growth under cold temperature conditions
CC (PubMed:24038679). {ECO:0000250|UniProtKB:P38344,
CC ECO:0000269|PubMed:24038679}.
CC -!- SUBUNIT: Can form homodimer. Interacts with RLP24, RLP24A, RPL24B, EBP1
CC and JJJ1. {ECO:0000269|PubMed:24603461}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P38344}.
CC -!- INDUCTION: By cold. {ECO:0000269|PubMed:24038679}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. When grown at 10 degrees Celsius, the double mutant
CC seedlings reil1-1 and reil2-1 show growth arrest at two cotyledon stage
CC and die. {ECO:0000269|PubMed:24038679}.
CC -!- SIMILARITY: Belongs to the REI1 family. {ECO:0000305}.
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DR EMBL; AF095588; AAD25324.1; -; mRNA.
DR EMBL; AC006403; AAD18121.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07585.1; -; Genomic_DNA.
DR EMBL; AY062620; AAL32698.1; -; mRNA.
DR EMBL; AY114695; AAM48014.1; -; mRNA.
DR PIR; T52423; T52423.
DR RefSeq; NP_180026.1; NM_128011.5.
DR AlphaFoldDB; Q9ZQ18; -.
DR IntAct; Q9ZQ18; 3.
DR STRING; 3702.AT2G24500.1; -.
DR iPTMnet; Q9ZQ18; -.
DR PaxDb; Q9ZQ18; -.
DR PRIDE; Q9ZQ18; -.
DR ProteomicsDB; 235033; -.
DR EnsemblPlants; AT2G24500.1; AT2G24500.1; AT2G24500.
DR GeneID; 816986; -.
DR Gramene; AT2G24500.1; AT2G24500.1; AT2G24500.
DR KEGG; ath:AT2G24500; -.
DR Araport; AT2G24500; -.
DR TAIR; locus:2061087; AT2G24500.
DR eggNOG; KOG2785; Eukaryota.
DR HOGENOM; CLU_018787_0_0_1; -.
DR InParanoid; Q9ZQ18; -.
DR OMA; PRRVEKN; -.
DR OrthoDB; 1383726at2759; -.
DR PhylomeDB; Q9ZQ18; -.
DR PRO; PR:Q9ZQ18; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZQ18; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR GO; GO:0005829; C:cytosol; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009631; P:cold acclimation; IMP:TAIR.
DR GO; GO:0090070; P:positive regulation of ribosome biogenesis; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IDA:UniProtKB.
DR GO; GO:0006364; P:rRNA processing; IMP:TAIR.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR041661; ZN622/Rei1/Reh1_Znf-C2H2.
DR InterPro; IPR040025; Znf622/Rei1/Reh1.
DR InterPro; IPR022755; Znf_C2H2_jaz.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR13182; PTHR13182; 1.
DR Pfam; PF12756; zf-C2H2_2; 1.
DR Pfam; PF12171; zf-C2H2_jaz; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SMART; SM00451; ZnF_U1; 2.
DR SUPFAM; SSF57667; SSF57667; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
PE 1: Evidence at protein level;
KW Cytoplasm; Metal-binding; Reference proteome; Repeat; Ribosome biogenesis;
KW Zinc; Zinc-finger.
FT CHAIN 1..395
FT /note="Cytoplasmic 60S subunit biogenesis factor REI1
FT homolog 2"
FT /id="PRO_0000435444"
FT ZN_FING 4..28
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 68..92
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 171..194
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255"
FT ZN_FING 222..249
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255"
SQ SEQUENCE 395 AA; 44987 MW; E3A44B650AE4DFA8 CRC64;
MSGLACNSCN KDFEDDAEQK FHYKSEWHRY NLKRKIAGVP GVTEALFEAR QAAIAQEKVK
AVEAPMLYSC GICNKGYRSS KAHEQHLKSK SHVLKASTST GEEDKAIIKQ LPPRRVEKNN
TAQLKGSIEE EESEDEWIEV DSDEDLDAEM NEDGEEEDMD EDGIEFELDP ACCLMCDKKH
KTIEKCMVHM HKFHGFFIPD IEYLKDPKGF LTYLGLKVKR DFVCLYCNEL CHPFSSLEAV
RKHMDAKGHC KVHYGDGGDE EDAELEEFYD YSSSYVNGDE NQMVVSGESV NTVELFGGSE
LVITKRTDNK VTSRTLGSRE FMRYYKQKPA PSSQKHIVNS LTSRYKMMGL ATVQSKEAIV
RMKVMREMNK RGAKSSVRLG MKSNVIRNLP NNVTY
