ID   RELE2_METJA             Reviewed;          91 AA.
AC   Q58319;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Putative toxin RelE2;
GN   Name=relE2; OrderedLocusNames=MJ0909;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=15718296; DOI=10.1093/nar/gki201;
RA   Pandey D.P., Gerdes K.;
RT   "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT   host-associated prokaryotes.";
RL   Nucleic Acids Res. 33:966-976(2005).
CC   -!- FUNCTION: Toxic component of a type II toxin-antitoxin (TA) system. Its
CC       cognate antitoxin is RelB2 (Potential). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RelE toxin family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98911.1; -; Genomic_DNA.
DR   PIR; E64413; E64413.
DR   RefSeq; WP_010870423.1; NC_000909.1.
DR   AlphaFoldDB; Q58319; -.
DR   SMR; Q58319; -.
DR   STRING; 243232.MJ_0909; -.
DR   EnsemblBacteria; AAB98911; AAB98911; MJ_0909.
DR   GeneID; 1451798; -.
DR   KEGG; mja:MJ_0909; -.
DR   eggNOG; arCOG01663; Archaea.
DR   HOGENOM; CLU_155761_5_1_2; -.
DR   OMA; YRIGFKY; -.
DR   OrthoDB; 125851at2157; -.
DR   PhylomeDB; Q58319; -.
DR   Proteomes; UP000000805; Chromosome.
DR   Gene3D; 3.30.2310.20; -; 1.
DR   InterPro; IPR007712; RelE/ParE_toxin.
DR   InterPro; IPR035093; RelE/ParE_toxin_dom_sf.
DR   Pfam; PF05016; ParE_toxin; 1.
DR   SUPFAM; SSF143011; SSF143011; 1.
DR   TIGRFAMs; TIGR02385; RelE_StbE; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..91
FT                   /note="Putative toxin RelE2"
FT                   /id="PRO_0000107099"
SQ   SEQUENCE   91 AA;  11146 MW;  4E42600B3466CD72 CRC64;
     MKQWKYLLKK SFIKDLKELP KNIQEKIKKL VFEEIPNKNN PPEIPNVKKL KGADSYYRIR
     VGDYRIGFKY ENGKIVFYRV LHRKQIYKRF P