ID   RELJ_MYCTO              Reviewed;          91 AA.
AC   P9WF24; L0TCA7; O50386; P65067;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Antitoxin RelJ;
DE   AltName: Full=Antitoxin YefM;
GN   Name=relJ; Synonyms=relB3, yefM; OrderedLocusNames=MT3465;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       A probable antitoxin for the putative mRNA interferase RelK (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK47804.1; -; Genomic_DNA.
DR   PIR; D70970; D70970.
DR   RefSeq; WP_003417757.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WF24; -.
DR   SMR; P9WF24; -.
DR   EnsemblBacteria; AAK47804; AAK47804; MT3465.
DR   GeneID; 45427356; -.
DR   KEGG; mtc:MT3465; -.
DR   PATRIC; fig|83331.31.peg.3724; -.
DR   HOGENOM; CLU_155837_1_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR006442; Antitoxin_Phd/YefM.
DR   InterPro; IPR036165; YefM-like_sf.
DR   Pfam; PF02604; PhdYeFM_antitox; 1.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Toxin-antitoxin system; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..91
FT                   /note="Antitoxin RelJ"
FT                   /id="PRO_0000428613"
SQ   SEQUENCE   91 AA;  10194 MW;  5A4140972F329F0A CRC64;
     MSISASEARQ RLFPLIEQVN TDHQPVRITS RAGDAVLMSA DDYDAWQETV YLLRSPENAR
     RLMEAVARDK AGHSAFTKSV DELREMAGGE E