ID   RELX_HYPSI              Reviewed;          81 AA.
AC   P81191;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Relaxin-like protein AGF;
DE   Contains:
DE     RecName: Full=Relaxin-like protein AGF B chain;
DE   Contains:
DE     RecName: Full=Relaxin-like protein AGF A chain;
OS   Hypanus sabinus (Atlantic stingray) (Dasyatis sabina).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Batoidea; Myliobatiformes; Dasyatidae; Hypanus.
OX   NCBI_TaxID=79690;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Alkaline gland;
RX   PubMed=9271504; DOI=10.1021/bi970393n;
RA   Buellesbach E.E., Schwabe C., Lacy E.R.;
RT   "Identification of a glycosylated relaxin-like molecule from the male
RT   Atlantic stingray, Dasyatis sabina.";
RL   Biochemistry 36:10735-10741(1997).
CC   -!- FUNCTION: Uncertain.
CC   -!- SUBUNIT: Heterodimer of a B chain and an A chain linked by two
CC       disulfide bonds.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the insulin family. {ECO:0000305}.
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DR   AlphaFoldDB; P81191; -.
DR   GlyConnect; 521; 1 N-Linked glycan (1 site).
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR016179; Insulin-like.
DR   InterPro; IPR036438; Insulin-like_sf.
DR   InterPro; IPR022353; Insulin_CS.
DR   Pfam; PF00049; Insulin; 1.
DR   SMART; SM00078; IlGF; 1.
DR   SUPFAM; SSF56994; SSF56994; 1.
DR   PROSITE; PS00262; INSULIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Glycoprotein; Hormone; Secreted.
FT   PEPTIDE         1..54
FT                   /note="Relaxin-like protein AGF B chain"
FT                   /id="PRO_0000016119"
FT   PEPTIDE         55..81
FT                   /note="Relaxin-like protein AGF A chain"
FT                   /id="PRO_0000016120"
FT   CARBOHYD        37
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /id="CAR_000159"
FT   DISULFID        14..66
FT                   /note="Interchain (between B and A chains)"
FT                   /evidence="ECO:0000250"
FT   DISULFID        26..79
FT                   /note="Interchain (between B and A chains)"
FT                   /evidence="ECO:0000250"
FT   DISULFID        65..70
FT                   /evidence="ECO:0000250"
FT   NON_CONS        54..55
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   81 AA;  9198 MW;  F616593DA19B990E CRC64;
     WPRGPDYTER RVMCGLQYVR AAISICGPNM QTMRPRNGSG PIVPPPDFLA MYGMARYKPP
     LSKKCCSTGC NREDFRGYCY L