REM1_SCHPO
ID REM1_SCHPO Reviewed; 402 AA.
AC O14332;
DT 24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 135.
DE RecName: Full=Meiosis-specific cyclin rem1;
GN Name=rem1; ORFNames=SPBC16E9.17c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION.
RX PubMed=16024772; DOI=10.1128/mcb.25.15.6330-6337.2005;
RA Malapeira J., Moldon A., Hidalgo E., Smith G.R., Nurse P., Ayte J.;
RT "A meiosis-specific cyclin regulated by splicing is required for proper
RT progression through meiosis.";
RL Mol. Cell. Biol. 25:6330-6337(2005).
CC -!- FUNCTION: Required for pre-meiotic DNA synthesis and S phase
CC progression. Regulates levels of meiotic intragenic recombination.
CC {ECO:0000269|PubMed:16024772}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
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DR EMBL; CU329671; CAB16909.1; -; Genomic_DNA.
DR PIR; T39591; T39591.
DR RefSeq; NP_595798.1; NM_001021699.2.
DR AlphaFoldDB; O14332; -.
DR SMR; O14332; -.
DR BioGRID; 276655; 81.
DR STRING; 4896.SPBC16E9.17c.1; -.
DR PaxDb; O14332; -.
DR EnsemblFungi; SPBC16E9.17c.1; SPBC16E9.17c.1:pep; SPBC16E9.17c.
DR GeneID; 2540118; -.
DR KEGG; spo:SPBC16E9.17c; -.
DR PomBase; SPBC16E9.17c; rem1.
DR VEuPathDB; FungiDB:SPBC16E9.17c; -.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_020695_2_4_1; -.
DR InParanoid; O14332; -.
DR OMA; YMLENTY; -.
DR PhylomeDB; O14332; -.
DR PRO; PR:O14332; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005635; C:nuclear envelope; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0006279; P:premeiotic DNA replication; IGI:PomBase.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0051445; P:regulation of meiotic cell cycle; NAS:PomBase.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cyclin; Meiosis; Reference proteome.
FT CHAIN 1..402
FT /note="Meiosis-specific cyclin rem1"
FT /id="PRO_0000080419"
SQ SEQUENCE 402 AA; 46004 MW; 64CBAE62C6439AEF CRC64;
MNSNNKRVAL QEISNYVSKS LNVKGWVNAQ VREISLQNGC SPSDKHFPSQ SWHGISSIEE
SQIQKDYDSF LASPLEEEIV FTEKQLLVDL DVCSISNVQS PNCSVSEFGI AIEESNDNCA
EEDEEEELQM RYSADESVSV EYAKEILSHM EKLEIRFMPD YRHMSAQPYY VTEMRASVIN
WIVGVHTCIN LLPESLFLSI NVLDRFLSLQ NVPASKMKLC GATALFIACK YEEIHPPTVK
DLEIVLEGEW IGEDICGMEK YMLMVLQYQL GWPGPVSFLR LLTIVNKWES QLRIMIKYFL
EVSLVEQRFS SLRASQLVAT CAYTGQSILQ EENWSNTLPQ ITGYDYMSLV SYVHLLLKCL
ENPFDHHYAI YSKYATPYFH GISRQVHDWI ATNTNLMAMD GS
