REM2_ARATH
ID REM2_ARATH Reviewed; 487 AA.
AC Q3E9T2; C0SVL0; Q9SB78;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 2.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=B3 domain-containing protein REM2;
DE AltName: Full=Protein REPRODUCTIVE MERISTEM 2;
GN Name=REM2; OrderedLocusNames=At4g31615; ORFNames=F28M20.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q3E9T2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3E9T2-2; Sequence=VSP_037987;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to an intron retention.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA19761.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g31620 has been split into 2 genes: At4g31615 and At4g31620.; Evidence={ECO:0000305};
CC Sequence=CAB79880.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g31620 has been split into 2 genes: At4g31615 and At4g31620.; Evidence={ECO:0000305};
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DR EMBL; AL031004; CAA19761.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161579; CAB79880.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE85937.1; -; Genomic_DNA.
DR EMBL; AB493713; BAH30551.1; -; mRNA.
DR PIR; T05108; T05108.
DR RefSeq; NP_680753.2; NM_148387.3. [Q3E9T2-1]
DR AlphaFoldDB; Q3E9T2; -.
DR SMR; Q3E9T2; -.
DR BioGRID; 14575; 3.
DR IntAct; Q3E9T2; 3.
DR STRING; 3702.AT4G31615.1; -.
DR iPTMnet; Q3E9T2; -.
DR PaxDb; Q3E9T2; -.
DR PRIDE; Q3E9T2; -.
DR EnsemblPlants; AT4G31615.1; AT4G31615.1; AT4G31615. [Q3E9T2-1]
DR GeneID; 829289; -.
DR Gramene; AT4G31615.1; AT4G31615.1; AT4G31615. [Q3E9T2-1]
DR KEGG; ath:AT4G31615; -.
DR Araport; AT4G31615; -.
DR TAIR; locus:504955488; AT4G31615.
DR HOGENOM; CLU_014437_0_0_1; -.
DR InParanoid; Q3E9T2; -.
DR OrthoDB; 697715at2759; -.
DR PhylomeDB; Q3E9T2; -.
DR PRO; PR:Q3E9T2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q3E9T2; baseline and differential.
DR Genevisible; Q3E9T2; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009561; P:megagametogenesis; IGI:TAIR.
DR GO; GO:0009555; P:pollen development; IGI:TAIR.
DR CDD; cd10017; B3_DNA; 3.
DR Gene3D; 2.40.330.10; -; 3.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR039218; REM_fam.
DR PANTHER; PTHR31674; PTHR31674; 1.
DR Pfam; PF02362; B3; 3.
DR SMART; SM01019; B3; 3.
DR SUPFAM; SSF101936; SSF101936; 3.
DR PROSITE; PS50863; B3; 3.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..487
FT /note="B3 domain-containing protein REM2"
FT /id="PRO_0000375096"
FT DNA_BIND 11..104
FT /note="TF-B3 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT DNA_BIND 151..247
FT /note="TF-B3 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT DNA_BIND 274..371
FT /note="TF-B3 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT REGION 379..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 477..487
FT /note="EKVSEINKILK -> MI (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_037987"
SQ SEQUENCE 487 AA; 55036 MW; 4608E0C71C51FBF4 CRC64;
MDDPAISSPT NKHFFVIVLH GHKSSPMIPA EFFSTYVEGK NHQSTKLKLT SDAFDRTWEV
KLNGRRFAGG WENFSTVHSL QDDDVVIFRE IGDMTFHVTA SGRSFCKLQY ISSDEDRADE
DDAWNVYSDS KNIVSKKKPR TEAESSSKNY YLVAHVTPSN LSRDRLYLIK AFARSNGLNE
RCCEIDLMNK HGKSWTLGLR YSTVNDQASI SGGWRDFCLV NGLEAGSFYR FKLVQNGERP
LLRLCYDTIP EEDCYKGNRK VNLSESASMK QGKFLTMTFK PYMLKSGQLR LSRPFAIENE
IKEAEDITLV DKNGGNWPSY VASGDGQGGK YYLAKGWRSF CAANRLKTGE TFTLEFVRGE
GTTPMLKFCS KSKDKIEQVP FDEGGETQEE TETRVKKRAR VSAERGSSRR NQASNKPNAD
PQNLQPGQPH CSISDQVQKV KQIIVDTLTG IKRIRSELER KGQKLEASIL EIDALGEKVS
EINKILK
