REMB_BACSU
ID REMB_BACSU Reviewed; 81 AA.
AC P37525;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 14-APR-2009, sequence version 2.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Extracellular matrix regulatory protein B {ECO:0000305};
DE AltName: Full=Regulator of the extracellular matrix B {ECO:0000303|PubMed:19363116};
GN Name=remB {ECO:0000303|PubMed:19363116}; Synonyms=yaaB;
GN OrderedLocusNames=BSU00050;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2987847; DOI=10.1093/nar/13.7.2251;
RA Moriya S., Ogasawara N., Yoshikawa H.;
RT "Structure and function of the region of the replication origin of the
RT Bacillus subtilis chromosome. III. Nucleotide sequence of some 10,000 base
RT pairs in the origin region.";
RL Nucleic Acids Res. 13:2251-2265(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA Ogasawara N., Nakai S., Yoshikawa H.;
RT "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT chromosome containing the replication origin.";
RL DNA Res. 1:1-14(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP SEQUENCE REVISION TO C-TERMINUS.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
RN [5]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=19363116; DOI=10.1128/jb.00278-09;
RA Winkelman J.T., Blair K.M., Kearns D.B.;
RT "RemA (YlzA) and RemB (YaaB) regulate extracellular matrix operon
RT expression and biofilm formation in Bacillus subtilis.";
RL J. Bacteriol. 191:3981-3991(2009).
CC -!- FUNCTION: Regulates the biosynthesis of the extracellular matrix and
CC the biofilm formation. May act as an enhancer of biofilm gene
CC expression. Acts in parallel to the pathway that governs SinR
CC derepression. {ECO:0000269|PubMed:19363116}.
CC -!- DISRUPTION PHENOTYPE: Mutation impairs pellicle formation, complex
CC colony architecture and motility inhibition in a sinR mutant
CC background. {ECO:0000269|PubMed:19363116}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA05241.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=X02369; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X02369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; D26185; BAA05241.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AL009126; CAB11781.2; -; Genomic_DNA.
DR PIR; S66035; S66035.
DR RefSeq; NP_387886.2; NC_000964.3.
DR RefSeq; WP_003219266.1; NZ_JNCM01000034.1.
DR AlphaFoldDB; P37525; -.
DR SMR; P37525; -.
DR STRING; 224308.BSU00050; -.
DR PaxDb; P37525; -.
DR PRIDE; P37525; -.
DR EnsemblBacteria; CAB11781; CAB11781; BSU_00050.
DR GeneID; 64301814; -.
DR GeneID; 939466; -.
DR KEGG; bsu:BSU00050; -.
DR PATRIC; fig|224308.179.peg.5; -.
DR eggNOG; ENOG5032Y6E; Bacteria.
DR OMA; MFIHLGG; -.
DR BioCyc; BSUB:BSU00050-MON; -.
DR PRO; PR:P37525; -.
DR Proteomes; UP000001570; Chromosome.
DR InterPro; IPR007169; RemA-like.
DR Pfam; PF04025; DUF370; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..81
FT /note="Extracellular matrix regulatory protein B"
FT /id="PRO_0000049428"
SQ SEQUENCE 81 AA; 9212 MW; 69688E6ECF720C1B CRC64;
MYIHLGDDFV VSTRDIVGIF DFKANMSPIV EEFLKKQKHK VVPSVNGTPK SIVVTVQNIY
YSPLSSSTLK KRAQFMFEID S
