ID   REN_BGYMV               Reviewed;         132 AA.
AC   P0CK35; P05173; Q67581;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   22-FEB-2012, sequence version 1.
DT   29-SEP-2021, entry version 16.
DE   RecName: Full=Replication enhancer protein;
DE            Short=REn;
DE   AltName: Full=15.6 kDa protein;
DE   AltName: Full=Protein AC3;
DE   AltName: Full=Protein AL3;
GN   ORFNames=AC3, AL3;
OS   Bean golden yellow mosaic virus (isolate Puerto Rico) (BGYMV) (Bean golden
OS   mosaic virus (isolate Puerto Rico)).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=222448;
OH   NCBI_TaxID=260885; Macroptilium lathyroides.
OH   NCBI_TaxID=108453; Malvastrum coromandelianum.
OH   NCBI_TaxID=3884; Phaseolus lunatus (Lima bean) (Phaseolus limensis).
OH   NCBI_TaxID=3885; Phaseolus vulgaris (Kidney bean) (French bean).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16593562; DOI=10.1073/pnas.82.11.3572;
RA   Howarth A.J., Caton J., Bossert M., Goodman R.M.;
RT   "Nucleotide sequence of bean golden mosaic virus and a model for gene
RT   regulation in geminiviruses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:3572-3576(1985).
CC   -!- FUNCTION: Increases viral DNA accumulation. Enhances infectivity and
CC       symptom expression (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homooligomer. Interacts with the replication-associated
CC       protein (REP). Interacts with host proliferating cell nuclear antigen
CC       (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1),
CC       and may thereby deregulate the host cell cycle. Oligomerization and
CC       interaction with PCNA are necessary for optimal replication enhancement
CC       (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae replication enhancer protein
CC       family. {ECO:0000305}.
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DR   EMBL; M10070; AAA46320.1; -; Genomic_DNA.
DR   Proteomes; UP000006572; Genome.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   InterPro; IPR000657; Gemini_AL3.
DR   Pfam; PF01407; Gemini_AL3; 1.
DR   PRINTS; PR00231; GEMCOATAL3.
PE   3: Inferred from homology;
KW   Host-virus interaction; Reference proteome.
FT   CHAIN           1..132
FT                   /note="Replication enhancer protein"
FT                   /id="PRO_0000222237"
SQ   SEQUENCE   132 AA;  15647 MW;  EEC61FEC7C107946 CRC64;
     MDSRTGENIT AHQAENSVFI WEVPNPLYFK IMRVEDPAYT RTRIYHIQIR FNHNLRKALD
     LHKAFLNFQV WTTSIQASGT TYLNRFRLLV LLYLHRLGVI GINNVIRAVQ FATNKSYVNT
     VLENHDIKYK FY