ID   REN_CALCV               Reviewed;         132 AA.
AC   Q96702;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Replication enhancer protein;
DE            Short=REn;
DE   AltName: Full=15.6 kDa protein;
DE   AltName: Full=Protein AC3;
DE   AltName: Full=Protein AL3;
GN   ORFNames=AC3, AL3;
OS   Cabbage leaf curl virus (isolate Jamaica) (CaLCuV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=345184;
OH   NCBI_TaxID=3712; Brassica oleracea (Wild cabbage).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Abouzid A.M., Hiebert E., Strandberg J.O.;
RT   "Cloning, identification and partial sequencing of a new geminivirus
RT   infecting Brassicaceae.";
RL   Phytopathology 82:1070-1070(1992).
CC   -!- FUNCTION: Increases viral DNA accumulation. Enhances infectivity and
CC       symptom expression (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homooligomer. Interacts with the replication-associated
CC       protein (REP). Interacts with host proliferating cell nuclear antigen
CC       (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1),
CC       and may thereby deregulate the host cell cycle. Oligomerization and
CC       interaction with PCNA are necessary for optimal replication enhancement
CC       (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae replication enhancer protein
CC       family. {ECO:0000305}.
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DR   EMBL; U65529; AAB17961.1; -; Genomic_DNA.
DR   Proteomes; UP000007622; Genome.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   InterPro; IPR000657; Gemini_AL3.
DR   Pfam; PF01407; Gemini_AL3; 1.
DR   PRINTS; PR00231; GEMCOATAL3.
PE   3: Inferred from homology;
KW   Host-virus interaction; Reference proteome.
FT   CHAIN           1..132
FT                   /note="Replication enhancer protein"
FT                   /id="PRO_0000323682"
SQ   SEQUENCE   132 AA;  15630 MW;  F87CE9812F9837D7 CRC64;
     MDSRTGESIT VAQAENSVFI WEVPNPLYFR IQRVEDPLYT RTRIYHIQVR FNHNLRKALD
     LRKAYFNFQV WTTSMRASGP TYLSRFKCLV MSHLDNLGVI GINHVIRAVR FATDRSYVTH
     VHENHVINFK IY