ID   REP2_SCHPO              Reviewed;         219 AA.
AC   Q09824;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Transcriptional activator protein rep2;
GN   Name=rep2; ORFNames=SPBC2F12.11c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7588609; DOI=10.1002/j.1460-2075.1995.tb00161.x;
RA   Nakashima N., Tanaka K., Sturm S., Okayama H.;
RT   "Fission yeast Rep2 is a putative transcriptional activator subunit for the
RT   cell cycle 'start' function of Res2-Cdc10.";
RL   EMBO J. 14:4794-4802(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Transcriptional activator which interacts with the mcb
CC       binding subunit complex formed by res2 and cdc10. Rep2 is required for
CC       the mitotic cell cycle start.
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DR   EMBL; X91044; CAA62504.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAB10158.1; -; Genomic_DNA.
DR   PIR; S59134; S59134.
DR   RefSeq; NP_595705.1; NM_001021602.2.
DR   AlphaFoldDB; Q09824; -.
DR   BioGRID; 276870; 11.
DR   STRING; 4896.SPBC2F12.11c.1; -.
DR   PaxDb; Q09824; -.
DR   EnsemblFungi; SPBC2F12.11c.1; SPBC2F12.11c.1:pep; SPBC2F12.11c.
DR   GeneID; 2540341; -.
DR   KEGG; spo:SPBC2F12.11c; -.
DR   PomBase; SPBC2F12.11c; rep2.
DR   VEuPathDB; FungiDB:SPBC2F12.11c; -.
DR   HOGENOM; CLU_1251309_0_0_1; -.
DR   PRO; PR:Q09824; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0030907; C:MBF transcription complex; EXP:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0062070; F:SAGA complex binding; IDA:PomBase.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:PomBase.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IMP:PomBase.
DR   GO; GO:0071931; P:positive regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:PomBase.
PE   4: Predicted;
KW   Activator; Cell cycle; Cell division; Metal-binding; Mitosis;
KW   Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..219
FT                   /note="Transcriptional activator protein rep2"
FT                   /id="PRO_0000097249"
FT   ZN_FING         177..197
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   219 AA;  24668 MW;  77F11A406E722656 CRC64;
     MHFADIPLSK PCLNNPPTYP WSSPILSSIA NPSLCDIVSS PSSVSSFASS DDFAFMNAYC
     LPIQQNHQFG SPVAASPNQQ PLVESQNRRN VTYASLVIGK LGIAQLIRQQ TDPPQIIHRK
     QDKGLMARVL SRSKKQEERE NHSSDARDAI KSALRRRMRR REGRVQKALR PTPNLICSKC
     NTTFNHSTAL MMHEATCLNQ VPFKLSDFFV EDVIDDWLF