ID   REP4_ECOLX              Reviewed;         340 AA.
AC   P13961;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 3.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Replication initiation protein;
DE   AltName: Full=Replication-associated protein;
GN   Name=repA1;
OS   Escherichia coli.
OG   Plasmid IncFI P307.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3032897; DOI=10.1128/jb.169.5.1836-1846.1987;
RA   Saadi S., Maas W.K., Hill D.F., Bergquist P.L.;
RT   "Nucleotide sequence analysis of RepFIC, a basic replicon present in IncFI
RT   plasmids P307 and F, and its relation to the RepA replicon of IncFII
RT   plasmids.";
RL   J. Bacteriol. 169:1836-1846(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SEQUENCE REVISION.
RX   PubMed=1857211; DOI=10.1111/j.1365-2958.1991.tb00767.x;
RA   Maas R., Oppenheim J., Saadi S., Fuchs T., Maas W.K.;
RT   "Isolation and properties of the RepA1 protein of the IncFII replicon,
RT   RepFIC.";
RL   Mol. Microbiol. 5:927-932(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SEQUENCE REVISION.
RA   Maas R.;
RL   Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; M16167; AAB17112.1; -; Genomic_DNA.
DR   PIR; B26870; B26870.
DR   PIR; S15225; S15225.
DR   RefSeq; WP_000840938.1; NZ_NXMG01000236.1.
DR   AlphaFoldDB; P13961; -.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:InterPro.
DR   InterPro; IPR003446; Plasmid_replication_init_RepA.
DR   Pfam; PF02387; IncFII_repA; 1.
PE   4: Predicted;
KW   DNA replication; Plasmid.
FT   CHAIN           1..340
FT                   /note="Replication initiation protein"
FT                   /id="PRO_0000068337"
FT   REGION          38..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   340 AA;  40147 MW;  4912A0BB1C925144 CRC64;
     MAERYISQRH WSQLPPEEQI RVWEDYEAGR ATTFLVEPER KRTKRRRGEH STKPKCENPT
     WYRPARYKAL SGQLGHAYNR LVKKDPVTGE QSLRMHMSRH PFYVQKRTFA GRKYAFRPEK
     QRLLDAVWPV LVSFSDAGTH TVGMSVSRLA KEISPKDSKG KVIPELEVTV SRLSRLLAEQ
     VRFGVLGMSE ETMWDRETRQ RLPRYVWITP AGWQMLGVDM VKLHEQQQKR LRESEIRQQL
     IREGVLREDE DISVHAARKR WYLQRSQDAL KHRRAKAAAR KRANLLKKLP ADQQIYEMSQ
     HILKRMPPDE AYWCTPERLQ QLAIRELYQL ELTLAAPPPH