ID   REP8_ECOLX              Reviewed;         343 AA.
AC   Q52346;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Replication initiation protein;
DE   AltName: Full=Replication-associated protein;
GN   Name=repA;
OS   Escherichia coli.
OG   Plasmid IncK R387.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1706708; DOI=10.1128/jb.173.7.2393-2397.1991;
RA   Praszkier J., Wei T., Siemering K., Pittard J.;
RT   "Comparative analysis of the replication regions of IncB, IncK, and IncZ
RT   plasmids.";
RL   J. Bacteriol. 173:2393-2397(1991).
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DR   EMBL; M93063; AAA98310.1; -; Genomic_DNA.
DR   PIR; B42382; B42382.
DR   RefSeq; WP_000907881.1; NZ_UGGC01000001.1.
DR   RefSeq; YP_003864264.1; NC_014477.1.
DR   AlphaFoldDB; Q52346; -.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:InterPro.
DR   InterPro; IPR003446; Plasmid_replication_init_RepA.
DR   Pfam; PF02387; IncFII_repA; 1.
PE   4: Predicted;
KW   DNA replication; Plasmid.
FT   CHAIN           1..343
FT                   /note="Replication initiation protein"
FT                   /id="PRO_0000068339"
FT   REGION          42..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   343 AA;  40344 MW;  A47EDAF95263941D CRC64;
     MAGLKNTSYN AVHWSQLAPE EQIRFWEDYE AGRATTFLVE PERKRTKRRR GEHSTKPKCE
     NPSWYRPERY KALSGQLGHA YNRLVKKDPV TGEQSLRMHM SLHPFYVQKR TYAGRKYAFR
     PEKQRLLDTI WPVLVSFSDA VTHTVGMSVS RLAREISPKD SKGKVIPELE VTVSRLSRLL
     AEQVRFGVLG VSEETLWDRE TRQRLPRYVW ITPAGWQMLG VDMVKLHEQQ QKRLRESEIR
     QQLIREGVLR EDEDISVHAA RKRWYLQRSQ DALKHRRAKA AASKRARRLK KLPADQQIHE
     MAEYLRKRLP PDEAYFCSDD HLKRLAIREL RQLELTLAAP PPH