ID   REPA1_BUCCC             Reviewed;         281 AA.
AC   Q5WQ00;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Probable replication-associated protein repA1;
GN   Name=repA1; OrderedLocusNames=BCc_PL2;
OS   Buchnera aphidicola subsp. Cinara cedri (strain Cc).
OG   Plasmid pLeu-BCc.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=372461;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Cc;
RX   PubMed=16413149; DOI=10.1016/j.gene.2005.10.043;
RA   Gil R., Sabater-Munoz B., Perez-Brocal V., Silva F.J., Latorre A.;
RT   "Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest
RT   genomes. A puzzling evolutionary story.";
RL   Gene 370:17-25(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Cc;
RX   PubMed=17038625; DOI=10.1126/science.1130441;
RA   Perez-Brocal V., Gil R., Ramos S., Lamelas A., Postigo M., Michelena J.M.,
RA   Silva F.J., Moya A., Latorre A.;
RT   "A small microbial genome: the end of a long symbiotic relationship?";
RL   Science 314:312-313(2006).
CC   -!- FUNCTION: This protein is essential for plasmid replication; it is
CC       involved in copy control functions. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IncFII RepA family. {ECO:0000305}.
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DR   EMBL; AY438025; AAR99733.1; -; Genomic_DNA.
DR   RefSeq; WP_012622902.1; NC_011878.1.
DR   AlphaFoldDB; Q5WQ00; -.
DR   SMR; Q5WQ00; -.
DR   STRING; 372461.41323036; -.
DR   EnsemblBacteria; AAR99733; AAR99733; AAR99733.
DR   KEGG; bcc:repA1; -.
DR   eggNOG; ENOG5032GWB; Bacteria.
DR   HOGENOM; CLU_084990_0_0_6; -.
DR   OMA; VARCELN; -.
DR   OrthoDB; 887062at2; -.
DR   Proteomes; UP000000669; Plasmid pLeu-BCc.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
DR   InterPro; IPR003446; Plasmid_replication_init_RepA.
DR   Pfam; PF02387; IncFII_repA; 1.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Plasmid copy control; Reference proteome.
FT   CHAIN           1..281
FT                   /note="Probable replication-associated protein repA1"
FT                   /id="PRO_0000274187"
SQ   SEQUENCE   281 AA;  33181 MW;  A8F479347F2C1D5A CRC64;
     MFKRKKYVDN PYPKFVQPKN HKKRPAFIRY AMRCAAQTDV ARNELYYTNP LKNPITGCVL
     HRKRRLNEHR ARALRAVVQA MLYYFNIASM LVMASVEKLS DVCGLSTYSS AGNKSITRAS
     RLITQFMEPM GLISCEKIWD KILGMYIPKI IYLKPLFFML FDISKIRLKR VRIKQLEWIN
     SQLKKKGEYP ITLLEIEKQA KEKHIHSALL FRKSKYIIKK QKNKAKKFLE LDEKYAKSYI
     LNNLVKKYST KELCKLGLTK LKRKVNCEYF RLKKLAQLPV V