ID   REPA2_BUCAI             Reviewed;         250 AA.
AC   Q9ZEY9; Q9JR85; Q9KGQ1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Probable replication-associated protein repA2;
GN   Name=repA2; OrderedLocusNames=BUpL03;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OG   Plasmid pLeu (pBAp1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9812361; DOI=10.1111/j.1574-6968.1998.tb13253.x;
RA   Silva F.J., van Ham R.C.H.J., Sabater B., Latorre A.;
RT   "Structure and evolution of the leucine plasmids carried by the
RT   endosymbiont (Buchnera aphidicola) from aphids of the family Aphididae.";
RL   FEMS Microbiol. Lett. 168:43-49(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: This protein is essential for plasmid replication; it is
CC       involved in copy control functions. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IncFII RepA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA95422.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ006878; CAA07304.1; -; Genomic_DNA.
DR   EMBL; AP001071; BAA95422.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_057967.1; NC_002253.1.
DR   AlphaFoldDB; Q9ZEY9; -.
DR   EnsemblBacteria; BAA95422; BAA95422; BAA95422.
DR   KEGG; buc:BUpL03; -.
DR   PATRIC; fig|107806.10.peg.9; -.
DR   HOGENOM; CLU_084990_0_0_6; -.
DR   OMA; CAMRAIV; -.
DR   Proteomes; UP000001806; Plasmid pLeu.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
DR   InterPro; IPR003446; Plasmid_replication_init_RepA.
DR   Pfam; PF02387; IncFII_repA; 2.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Plasmid copy control; Reference proteome.
FT   CHAIN           1..250
FT                   /note="Probable replication-associated protein repA2"
FT                   /id="PRO_0000216230"
FT   CONFLICT        87
FT                   /note="N -> D (in Ref. 1; CAA07304)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   250 AA;  28740 MW;  81F66226A38EA7B0 CRC64;
     MPRKNYIYNL KPFFNPSKNE RKKSTFICYA MKKVSEIDVA RSHLNRALLP IDPKTGNVLP
     RFRRLNKHRA CAMRAIVPAM LYYFNINSKL VEASIEKLAD ECGLSTLSDS GNKSITRASR
     LISEFLEPMG FVKCKKINSK SMSNYIPKKI FLTPMFFMLC GISPSEINHF LSKKIKPLKK
     LKKQEKSAFI SFTDMKIISQ LDERSARTKI LNALINYYTA SELTKIGPKG LKKKIDIEYS
     NLCNLYKKKS