ID   REPA2_BUCAP             Reviewed;         250 AA.
AC   O85062; Q9R863;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Probable replication-associated protein repA2;
GN   Name=repA2; OrderedLocusNames=BUsg_PL3;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OG   Plasmid pLeu-Sg (pBSg1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9812361; DOI=10.1111/j.1574-6968.1998.tb13253.x;
RA   Silva F.J., van Ham R.C.H.J., Sabater B., Latorre A.;
RT   "Structure and evolution of the leucine plasmids carried by the
RT   endosymbiont (Buchnera aphidicola) from aphids of the family Aphididae.";
RL   FEMS Microbiol. Lett. 168:43-49(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=9873079; DOI=10.1007/pl00006447;
RA   Baumann L., Baumann P., Moran N.A., Sandstroem J.P., Thao M.L.;
RT   "Genetic characterization of plasmids containing genes encoding enzymes of
RT   leucine biosynthesis in endosymbionts (Buchnera) of aphids.";
RL   J. Mol. Evol. 48:77-85(1999).
CC   -!- FUNCTION: This protein is essential for plasmid replication; it is
CC       involved in copy control functions. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IncFII RepA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ006876; CAA07295.1; -; Genomic_DNA.
DR   EMBL; AF041836; AAD12592.1; -; Genomic_DNA.
DR   RefSeq; NP_047179.1; NC_001910.1.
DR   AlphaFoldDB; O85062; -.
DR   OMA; CAMRAIV; -.
DR   Proteomes; UP000000416; Plasmid pLeu-Sg.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
DR   InterPro; IPR003446; Plasmid_replication_init_RepA.
DR   Pfam; PF02387; IncFII_repA; 2.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Plasmid copy control.
FT   CHAIN           1..250
FT                   /note="Probable replication-associated protein repA2"
FT                   /id="PRO_0000216231"
FT   CONFLICT        140
FT                   /note="Q -> H (in Ref. 1; CAA07295)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        146
FT                   /note="I -> T (in Ref. 1; CAA07295)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        227
FT                   /note="P -> L (in Ref. 1; CAA07295)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   250 AA;  28953 MW;  BD6B3DBF94CDB893 CRC64;
     MPRKNYICNL KPVFNPPKNE KKRSNFIDYA MKKASEIDVA RSKLNYTLLA IDPKTGNILP
     RFRRLNEHRA CAMRAIVLAM LYYWNTNSNL VEASIEKLSD ECGLSTFSNS GNKSITRASR
     LITDFMEPMG FIKCKRKKTQ SSSNYIPKKI FLTSNFFMLF HISQSTINQY LSEQKQSIKN
     LKKEKKIFIS FSDIRVISKL DEKAARNKIL NALIKYYSAS ELTKIGPQGL KKKIDIEYSN
     LCKLYKKNNK