ID   REPA_ECOLX              Reviewed;         288 AA.
AC   P05833;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Protein RepA;
GN   Name=repA;
OS   Escherichia coli.
OG   Plasmid mini-Rts1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6325393; DOI=10.1128/jb.158.1.307-312.1984;
RA   Kamio Y., Tabuchi A., Itoh Y., Katagiri H., Terawaki Y.;
RT   "Complete nucleotide sequence of mini-Rts1 and its copy mutant.";
RL   J. Bacteriol. 158:307-312(1984).
CC   -!- FUNCTION: This protein is essential for plasmid replication; it is
CC       involved in copy control functions.
CC   -!- SIMILARITY: Belongs to the initiator RepB protein family.
CC       {ECO:0000305}.
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DR   EMBL; K00053; AAA91589.1; -; Genomic_DNA.
DR   PIR; A23222; BVECRA.
DR   AlphaFoldDB; P05833; -.
DR   SMR; P05833; -.
DR   DIP; DIP-16934N; -.
DR   IntAct; P05833; 1.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Plasmid copy control.
FT   CHAIN           1..288
FT                   /note="Protein RepA"
FT                   /id="PRO_0000068300"
SQ   SEQUENCE   288 AA;  32930 MW;  E84CC71A456400E6 CRC64;
     METQLVISDV LFGNTEEKQK PLTVNELNTI QPVAFMRLGL FVPKPSRSSD YSPMIDVSEL
     SSTFEFARLE GFTDIKITGE RLDMDTDFKV WIGIVKAFSK YGISSNRIKL KFSEFAKDCG
     FPGKKLDKKL RAHIDESLRK IRGKSISFKR GKDSQSAYHT GLIKIAYFNA DTDVVELEAD
     ERLWELYYFD YRVVLQLHAI KALPRLEVAQ ALYTFLASLP SNPAPISFER LRERLSLISQ
     VKEQNRIIKK AITKLIDIGN LDASMVKKGQ ENYLIIHKRS PKLSVINE