ID   REPB_BACSP              Reviewed;         235 AA.
AC   P0A0C4; P05061;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   03-AUG-2022, entry version 25.
DE   RecName: Full=Replication protein;
GN   Name=repB;
OS   Bacillus sp.
OG   Plasmid pRBH1, and Plasmid pTB913.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1409;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=pRBH1;
RX   PubMed=3007933; DOI=10.1007/bf00330534;
RA   Mueller R.E., Ano T., Imanaka T., Aiba S.;
RT   "Complete nucleotide sequences of Bacillus plasmids pUB110dB, pRBH1 and its
RT   copy mutants.";
RL   Mol. Gen. Genet. 202:169-171(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=pTB913;
RX   PubMed=2677995; DOI=10.1093/nar/17.18.7283;
RA   van der Lelie D., Bron S., Venema G., Oskam L.;
RT   "Similarity of minus origins of replication and flanking open reading
RT   frames of plasmids pUB110, pTB913 and pMV158.";
RL   Nucleic Acids Res. 17:7283-7294(1989).
CC   -!- FUNCTION: Produces a single-strand nick in a specific site of the
CC       plasmid, and this nick results in single-strand replication by rolling
CC       circle mechanism.
CC   -!- SIMILARITY: Belongs to the Gram-positive plasmids replication protein
CC       type 1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA33714.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X03409; CAA27143.1; -; Genomic_DNA.
DR   EMBL; X15670; CAA33714.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; P0A0C4; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR000989; Rep.
DR   Pfam; PF01446; Rep_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid.
FT   CHAIN           1..235
FT                   /note="Replication protein"
FT                   /id="PRO_0000068318"
FT   BINDING         149
FT                   /ligand="DNA"
FT                   /ligand_id="ChEBI:CHEBI:16991"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   235 AA;  27895 MW;  247C0371D8F6201A CRC64;
     MKHGIQSQKV VAEVIKQKPT VRWLFLTLTV KNVYDGEELN KSLSDMAQGF RRMMQYKKIN
     KNLVGFMRAT EVTINNKDNS YNQHMHVLVC VEPTYFKNTE NYVNQKQWIQ FWKKAMKLDY
     DPNVKVQMIR PKNKYKSDIQ SAIDETAKYP VKDTDFMTDD EEKNLKRLSD LEEGLHRKRL
     ISYGGLLKEI HKKLNLDDTE EGDLIHTDDD EKADEDGFSI IAMWNWERKN YFIKE