ID   REPE2_SALTI             Reviewed;         251 AA.
AC   P62539; P33456;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Replication initiation protein;
DE            Short=Protein E;
DE            Short=Protein rep;
GN   Name=repE; Synonyms=rep; OrderedLocusNames=HCM1.137;
OS   Salmonella typhi.
OG   Plasmid pHCM1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
CC   -!- SIMILARITY: Belongs to the initiator RepB protein family.
CC       {ECO:0000305}.
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DR   EMBL; AL513383; CAD09735.1; -; Genomic_DNA.
DR   RefSeq; NP_058391.1; NC_002305.1.
DR   RefSeq; NP_569349.1; NC_003384.1.
DR   RefSeq; WP_000807689.1; NZ_PJSB01000061.1.
DR   AlphaFoldDB; P62539; -.
DR   SMR; P62539; -.
DR   KEGG; sty:HCM1.137; -.
DR   PATRIC; fig|220341.7.peg.5180; -.
DR   HOGENOM; CLU_047367_3_0_6; -.
DR   OMA; ETHDSEN; -.
DR   PRO; PR:P62539; -.
DR   Proteomes; UP000000541; Plasmid pHCM1.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR000525; Initiator_Rep_prot.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01051; Rep_3; 1.
DR   SUPFAM; SSF46785; SSF46785; 2.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Plasmid copy control.
FT   CHAIN           1..251
FT                   /note="Replication initiation protein"
FT                   /id="PRO_0000068299"
SQ   SEQUENCE   251 AA;  29378 MW;  33DE916FA68178DF CRC64;
     MAEIAVINHK KRKNSPRIVQ SNELTEAAYS LSRDQKRLLY LFVHQIRKSD GSLQEHDGIC
     EIHVAKYAET FGLTSAEASK DIRQALKGFA GKEVVFYRPE EDAGDEKGYE SFPWFIKRAH
     SPSRGLYSVH INPYLIPFFI GLQNRFTQFR LSETKEITNP YAMRLYESLC QYRKPDGSGV
     VSLKIDWIME RYQLPQSYQR MPDFRRRFLK ASVDEINSRT PMRLSYIEKK KGRQTTHIVF
     SFRDITSMTI E