ID   REPLM_STAAU             Reviewed;         158 AA.
AC   P0A0C8; P13969;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Replication and maintenance protein;
DE   AltName: Full=Plasmid replication protein;
GN   Name=repL; Synonyms=rep;
OS   Staphylococcus aureus.
OG   Plasmid pE5, and Plasmid pT48.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=pE5;
RX   PubMed=2822666; DOI=10.1128/jb.169.11.5131-5139.1987;
RA   Projan S.J., Monod M., Narayanan C.S., Dubnau D.;
RT   "Replication properties of pIM13, a naturally occurring plasmid found in
RT   Bacillus subtilis, and of its close relative pE5, a plasmid native to
RT   Staphylococcus aureus.";
RL   J. Bacteriol. 169:5131-5139(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=T48; PLASMID=pT48;
RX   PubMed=3141573; DOI=10.1099/00221287-134-3-697;
RA   Catchpole I., Thomas C., Davies A., Dyke K.G.H.;
RT   "The nucleotide sequence of Staphylococcus aureus plasmid pT48 conferring
RT   inducible macrolide-lincosamide-streptogramin B resistance and comparison
RT   with similar plasmids expressing constitutive resistance.";
RL   J. Gen. Microbiol. 134:697-709(1988).
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DR   EMBL; M17990; AAA98227.1; -; Genomic_DNA.
DR   PIR; A29827; A29827.
DR   RefSeq; NP_040474.1; NC_001395.1.
DR   RefSeq; WP_000664727.1; NZ_WNWJ01000023.1.
DR   RefSeq; YP_001901401.1; NC_010685.1.
DR   RefSeq; YP_001901403.1; NC_010686.1.
DR   RefSeq; YP_006937186.1; NC_013291.1.
DR   RefSeq; YP_006937475.1; NC_013305.1.
DR   RefSeq; YP_006958100.1; NC_019139.1.
DR   RefSeq; YP_006958111.1; NC_019143.1.
DR   RefSeq; YP_006958490.1; NC_018969.1.
DR   RefSeq; YP_009060502.1; NC_024963.1.
DR   RefSeq; YP_271814.1; NC_007209.1.
DR   AlphaFoldDB; P0A0C8; -.
DR   SMR; P0A0C8; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR008813; Plasmid_replication_RepL.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF05732; RepL; 1.
DR   SMART; SM00419; HTH_CRP; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   4: Predicted;
KW   DNA replication; Plasmid.
FT   CHAIN           1..158
FT                   /note="Replication and maintenance protein"
FT                   /id="PRO_0000068432"
SQ   SEQUENCE   158 AA;  18079 MW;  60E337A2A024455C CRC64;
     MKERYGTVYK GSQRLIDEES GEVIEVDKLY RKQTSGNFVK AYIVQLISML DMIGGKKLKI
     VNYILDNVHL SNNTMIATTR EIAKATGTSL QTVITTLKIL EEGNIIKRKT GVLMLNPELL
     MRGDDQKQKY LLLEFGNFEQ EANEKQENAL SDYYSFKD