ID   REPP_ONYPE              Reviewed;         377 AA.
AC   Q8G8D1;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Replication protein;
GN   Name=rep; OrderedLocusNames=PAM_790;
OS   Onion yellows phytoplasma (strain OY-M).
OG   Plasmid pOYM, and Plasmid pOYNIM.
OC   Bacteria; Tenericutes; Mollicutes; Acholeplasmatales; Acholeplasmataceae;
OC   Candidatus Phytoplasma; Candidatus Phytoplasma asteris.
OX   NCBI_TaxID=262768;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OY-M, and OY-NIM;
RX   PubMed=12426107; DOI=10.1016/s0378-1119(02)00975-7;
RA   Nishigawa H., Oshima K., Kakizawa S., Jung H.Y., Kuboyama T., Miyata S.,
RA   Ugaki M., Namba S.;
RT   "A plasmid from a non-insect-transmissible line of a phytoplasma lacks two
RT   open reading frames that exist in the plasmid from the wild-type line.";
RL   Gene 298:195-201(2002).
CC   -!- FUNCTION: Is essential for plasmid replication. Nicks the positive
CC       strand at the plus origin of replication (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Gram-positive plasmids replication protein
CC       type 2 family. {ECO:0000305}.
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DR   EMBL; AB061723; BAC23024.1; -; Genomic_DNA.
DR   EMBL; AB061724; BAC23025.1; -; Genomic_DNA.
DR   RefSeq; YP_002600752.1; NC_012089.1.
DR   RefSeq; YP_002600757.1; NC_012090.1.
DR   RefSeq; YP_006959604.1; NC_019170.1.
DR   RefSeq; YP_006959608.1; NC_019171.1.
DR   RefSeq; YP_006959611.1; NC_019172.1.
DR   RefSeq; YP_006959614.1; NC_019173.1.
DR   AlphaFoldDB; Q8G8D1; -.
DR   OMA; MECIFIT; -.
DR   Proteomes; UP000002523; Plasmid pOYM.
DR   GO; GO:0005727; C:extrachromosomal circular DNA; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003916; F:DNA topoisomerase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002631; Plasmid_rep.
DR   Pfam; PF01719; Rep_2; 1.
DR   Pfam; PF00910; RNA_helicase; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Plasmid;
KW   Reference proteome.
FT   CHAIN           1..377
FT                   /note="Replication protein"
FT                   /id="PRO_0000068329"
FT   BINDING         204..211
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  44377 MW;  D969193130C4FA83 CRC64;
     MKLRICELVI NKTLITKTKI ETILETKKKA IQNYAYILHD KDIYQNEKEA QLNGKKVGDI
     KAPHWHIYLR FNYSQDTKHI SQWFNTQENF VSKIKGRFSD ALMYMIHANR LDKHQYDEKE
     VVSNFDWKSE AQQDIFNRKY KMDARLKDIL LKIHSGEIKE YNINDNINIL ENNIYATAIE
     KAFKFRIRDL KKKVRQMECI FITGLSGSGK STLAKKIAED KNYEAYISSG SNDILDDYCG
     EECIILDDLR SNCLGLSDLL KMLDNNTASS VKSRYKNKVL ECQLIIITTV KSIDDFFEDI
     FRKDESIIQL KRRCKLHIKI DSKYIYYSVW NPIEMKYDLI EKKPNNLLND FQIKSLSKKE
     AKDYIKSISN IDLDKDC