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REP_AHEBV
ID   REP_AHEBV               Reviewed;         474 AA.
AC   A0A1P8YT89;
DT   07-NOV-2018, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2017, sequence version 1.
DT   02-JUN-2021, entry version 18.
DE   RecName: Full=Replication-associated protein;
DE            Short=Rep;
OS   Avon-Heathcote Estuary associated kieseladnavirus (AHEaBV) (Avon-Heathcote
OS   Estuary associated bacilladnavirus).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes;
OC   Baphyvirales; Bacilladnaviridae; Kieseladnavirus.
OX   NCBI_TaxID=2169964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AHEaBavV1;
RX   PubMed=28189969; DOI=10.1016/j.virol.2017.02.001;
RA   Kazlauskas D., Dayaram A., Kraberger S., Goldstien S., Varsani A.,
RA   Krupovic M.;
RT   "Evolutionary history of ssDNA bacilladnaviruses features horizontal
RT   acquisition of the capsid gene from ssRNA nodaviruses.";
RL   Virology 504:114-121(2017).
CC   -!- FUNCTION: Plays an essential for the replication of viral DNA.
CC       Presumably cleaves viral genomic dsRNA replicative form to initiate
CC       rolling circle replication. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000305}.
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DR   EMBL; KY405008; AQA27298.1; -; Genomic_DNA.
DR   RefSeq; YP_009345097.1; NC_033744.1.
DR   GeneID; 30999667; -.
DR   KEGG; vg:30999667; -.
DR   Proteomes; UP000214340; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR   Pfam; PF00910; RNA_helicase; 1.
PE   4: Predicted;
KW   Host nucleus; Reference proteome.
FT   CHAIN           1..474
FT                   /note="Replication-associated protein"
FT                   /id="PRO_0000445651"
FT   REGION          455..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           248..255
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
SQ   SEQUENCE   474 AA;  53333 MW;  654213345DAF82D8 CRC64;
     MFLAAIHVIT FFISENSKSF YTMSTPTSAF NAMLDDIGIE IQDDISALCS TLADPSDAEP
     APPVHDVDDL LASVGPDKRK KIRSGLLTIH PPSSHPSWLK PETWFPQCDD ILEIWCAKFE
     KGEDTGNLHV HIYFKLKHSN TIRFELLQKW ITKHVTGFDF KPQRSATKNS TQCVVNYVLK
     PETSVGDPFI WNASCAFDQK TWDARHKGKG KKQEIIDHIM ARDWTLSWAS LVHESDESRA
     LLADCGWGKR FQEDRAAAQP RRKIKDVVIL YGAAGTGKTT MAMDWDSKPD ETTKARYYRR
     SCDEDFWGGG ATAYNGQRVI HYDEFGGQEK FASLKEITSI GLPGPPVKVK GSGRDLNHDT
     VVFTSNVHPA GWYKGVWAKD PHQFKPFQRR VTKVLFFPRE RPDGTENVPS DGNPAHFVDQ
     TPEWVAFGDN LDLAIEHAES CWPLPATIED DGGGAFAPGF SLTSEPEPKR RRFF
 
 
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