REP_AHEBV
ID REP_AHEBV Reviewed; 474 AA.
AC A0A1P8YT89;
DT 07-NOV-2018, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2017, sequence version 1.
DT 02-JUN-2021, entry version 18.
DE RecName: Full=Replication-associated protein;
DE Short=Rep;
OS Avon-Heathcote Estuary associated kieseladnavirus (AHEaBV) (Avon-Heathcote
OS Estuary associated bacilladnavirus).
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes;
OC Baphyvirales; Bacilladnaviridae; Kieseladnavirus.
OX NCBI_TaxID=2169964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AHEaBavV1;
RX PubMed=28189969; DOI=10.1016/j.virol.2017.02.001;
RA Kazlauskas D., Dayaram A., Kraberger S., Goldstien S., Varsani A.,
RA Krupovic M.;
RT "Evolutionary history of ssDNA bacilladnaviruses features horizontal
RT acquisition of the capsid gene from ssRNA nodaviruses.";
RL Virology 504:114-121(2017).
CC -!- FUNCTION: Plays an essential for the replication of viral DNA.
CC Presumably cleaves viral genomic dsRNA replicative form to initiate
CC rolling circle replication. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000305}.
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DR EMBL; KY405008; AQA27298.1; -; Genomic_DNA.
DR RefSeq; YP_009345097.1; NC_033744.1.
DR GeneID; 30999667; -.
DR KEGG; vg:30999667; -.
DR Proteomes; UP000214340; Genome.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR Pfam; PF00910; RNA_helicase; 1.
PE 4: Predicted;
KW Host nucleus; Reference proteome.
FT CHAIN 1..474
FT /note="Replication-associated protein"
FT /id="PRO_0000445651"
FT REGION 455..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 248..255
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
SQ SEQUENCE 474 AA; 53333 MW; 654213345DAF82D8 CRC64;
MFLAAIHVIT FFISENSKSF YTMSTPTSAF NAMLDDIGIE IQDDISALCS TLADPSDAEP
APPVHDVDDL LASVGPDKRK KIRSGLLTIH PPSSHPSWLK PETWFPQCDD ILEIWCAKFE
KGEDTGNLHV HIYFKLKHSN TIRFELLQKW ITKHVTGFDF KPQRSATKNS TQCVVNYVLK
PETSVGDPFI WNASCAFDQK TWDARHKGKG KKQEIIDHIM ARDWTLSWAS LVHESDESRA
LLADCGWGKR FQEDRAAAQP RRKIKDVVIL YGAAGTGKTT MAMDWDSKPD ETTKARYYRR
SCDEDFWGGG ATAYNGQRVI HYDEFGGQEK FASLKEITSI GLPGPPVKVK GSGRDLNHDT
VVFTSNVHPA GWYKGVWAKD PHQFKPFQRR VTKVLFFPRE RPDGTENVPS DGNPAHFVDQ
TPEWVAFGDN LDLAIEHAES CWPLPATIED DGGGAFAPGF SLTSEPEPKR RRFF