ID   REP_BIFLO               Reviewed;         297 AA.
AC   Q8GN33;
DT   16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Probable replication protein rep;
GN   Name=rep; OrderedLocusNames=BL1821;
OS   Bifidobacterium longum (strain NCC 2705).
OG   Plasmid pBLO1.
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=206672;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCC 2705;
RX   PubMed=12381787; DOI=10.1073/pnas.212527599;
RA   Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G.,
RA   Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.;
RT   "The genome sequence of Bifidobacterium longum reflects its adaptation to
RT   the human gastrointestinal tract.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002).
CC   -!- SIMILARITY: Belongs to the initiator RepB protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF540971; AAN31777.1; -; Genomic_DNA.
DR   RefSeq; NP_862282.1; NC_004943.1.
DR   RefSeq; WP_011117009.1; NC_004943.1.
DR   AlphaFoldDB; Q8GN33; -.
DR   SMR; Q8GN33; -.
DR   PRIDE; Q8GN33; -.
DR   EnsemblBacteria; AAN31777; AAN31777; AAN31777.
DR   KEGG; blo:rep; -.
DR   PATRIC; fig|206672.9.peg.1868; -.
DR   HOGENOM; CLU_059708_0_1_11; -.
DR   OMA; NYMFEDS; -.
DR   Proteomes; UP000000439; Plasmid pBLO1.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR000525; Initiator_Rep_prot.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01051; Rep_3; 1.
DR   SUPFAM; SSF46785; SSF46785; 2.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Reference proteome.
FT   CHAIN           1..297
FT                   /note="Probable replication protein rep"
FT                   /id="PRO_0000068310"
SQ   SEQUENCE   297 AA;  34068 MW;  B9F1971A5744BC7B CRC64;
     MSNEIVKFSN QFNNVALKKF DAVHLDVLMA IASRVRERGT ATVEFSFEEL RGLMRLKQNL
     TNKQLADKIV QTNARLLALN YMFEDSGKII QFALFTVFET DPANQTLEVS VNERFAFLLN
     DLTSQFTRFE LAEFADLKSK YAKEFYRRAK QYRSSGIWKV SRDEFCRLLN VSKSTSDSVS
     NLNRVVLKPI VEECGPLLGL KIERQYAKRR LSGFVFTFAR ETPPVIDARP VKAKEEQDSG
     HWTSVAGYGE VFTTTELFDV TAARDHFDGT VDAGECRYCR YDARNRERHA RNAGTLF