ID   REP_CPBDV               Reviewed;         484 AA.
AC   W6JGV7;
DT   07-NOV-2018, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   23-FEB-2022, entry version 25.
DE   RecName: Full=Replication-associated protein;
DE            Short=Rep;
DE   AltName: Full=Viral protein 3;
DE            Short=VP3;
OS   Chaetoceros protobacilladnavirus 2 (Chaetoceros sp. DNA virus 7).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes;
OC   Baphyvirales; Bacilladnaviridae; Protobacilladnavirus.
OX   NCBI_TaxID=2170141;
OH   NCBI_TaxID=49237; Chaetoceros.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND FUNCTION.
RC   STRAIN=Csp07DNAV;
RX   PubMed=24358139; DOI=10.1371/journal.pone.0082013;
RA   Kimura K., Tomaru Y.;
RT   "Isolation and Characterization of a Single-Stranded DNA Virus Infecting
RT   the Marine Diatom Chaetoceros sp. Strain SS628-11 Isolated from Western
RT   Japan.";
RL   PLoS ONE 8:E82013-E82013(2013).
CC   -!- FUNCTION: Plays an essential for the replication of viral DNA.
CC       Presumably cleaves viral genomic dsRNA replicative form to initiate
CC       rolling circle replication. {ECO:0000303|PubMed:24358139, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000305}.
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DR   EMBL; AB844272; BAO48208.1; -; Genomic_DNA.
DR   RefSeq; YP_009001777.1; NC_023441.1.
DR   GeneID; 18266919; -.
DR   KEGG; vg:18266919; -.
DR   Proteomes; UP000052105; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   DNA replication; Host nucleus; Reference proteome; Viral DNA replication.
FT   CHAIN           1..484
FT                   /note="Replication-associated protein"
FT                   /id="PRO_0000445642"
FT   MOTIF           146..153
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
SQ   SEQUENCE   484 AA;  56228 MW;  97EE0DB051152627 CRC64;
     MSAPLSIEQD DLLTDDLKSW LSDIDFSNDN EEAIEMEPSD IEMSSPPIDI ETSPPEEADV
     NLDDTWATVQ KNGNNKLNRF ILTFFPSDMD TKWLEPETYF ENSPNKFDCW TGQYEYCPDT
     GKLHAHIYIE CNHKHRIRFN VFHREIRKYH QSVQLQLAKR ASKKQRQSAI NYVTADFKRA
     PGSLVFRWEH NKFPSDFDPK CVNKKSKSDK VSKDEQHETQ RLWIESKPRH WTWDQIVHEN
     EESKKLLFGC TAGEKYHKGR HAEDARRTIN DVIIFYGAGG TGKTTEAQAW GSEDEPVQEC
     RYYRRNPDDG AFWGGGRTCY KGQRIVHYEE FAGQEAFGRL KEVCDIGKHG PAVNVKNGGA
     LLNHDTVIFT SNIHPAGWFH KLWESDPKQW MPFERRITQV RFYPSHRADG SLNQPDENNP
     PYFIDQTEEF RQFVGDYDKA KEHAELHWPL KEAPEPTAQV FVPGRSHGVT ENTFFEYCKT
     GRAP