ID   REP_STRP2               Reviewed;         320 AA.
AC   O52776;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Protein rep;
DE   AltName: Full=Replication protein;
GN   Name=rep; OrderedLocusNames=SPD_2300;
OS   Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466).
OG   Plasmid pDP1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=373153;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D39 / NCTC 7466;
RX   PubMed=9887308; DOI=10.1006/plas.1998.1364;
RA   Oggioni M.R., Iannelli F., Pozzi G.;
RT   "Characterization of cryptic plasmids pDP1 and pSMB1 of Streptococcus
RT   pneumoniae.";
RL   Plasmid 41:70-72(1999).
CC   -!- FUNCTION: Produces a single-strand nick in a specific site of the
CC       plasmid, and this nick results in single-strand replication by rolling
CC       circle mechanism.
CC   -!- SIMILARITY: Belongs to the Gram-positive plasmids replication protein
CC       type 1 family. {ECO:0000305}.
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DR   EMBL; AF047696; AAD12155.1; -; Genomic_DNA.
DR   RefSeq; NP_863586.1; NC_005022.1.
DR   RefSeq; WP_011117663.1; NC_005022.1.
DR   AlphaFoldDB; O52776; -.
DR   OMA; WFLELTR; -.
DR   Proteomes; UP000001452; Plasmid pDP1.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR000989; Rep.
DR   Pfam; PF01446; Rep_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid.
FT   CHAIN           1..320
FT                   /note="Protein rep"
FT                   /id="PRO_0000275929"
SQ   SEQUENCE   320 AA;  37533 MW;  FC3D9945AAB17EC2 CRC64;
     MEKWENQDKI LLDKNKRGKD RNWRGRKLLS LKLADIFKEL GYRETLIERV ETCGDTLRFI
     RREDGSLRLY QAYFCKNKLC PMCNWRRSMK YSYQTSQIVD EAIKEQPKGR FLFLTLTVKN
     VPGKELNATI SQLTQSFDRL FRRAKVKKNL IGFLRSVEVT HNQEEETYHP HIHVLMMVKS
     SYFSGAGDNY VSQEEWGRMW EQSLKVDYVP MVDIRSVKEI GKGLKGAILE TAKYPIKPIK
     LDVENKQVVG DLYNGLYRKR QLGYGGLFKE IRKRLQLSNV ENGDLVYTSD DNDEMSKGTK
     IVAIWNATKQ NYFVKNKGWN