REQ1_ECOLI
ID REQ1_ECOLI Reviewed; 127 AA.
AC Q47274; Q2MBM9;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Prophage antitermination protein Q homolog QuuD {ECO:0000305};
DE AltName: Full=Antitermination protein Q homolog from lambdoid prophage DLP12;
GN Name=quuD; Synonyms=ybcQ; OrderedLocusNames=b0551, JW0539;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=8648624; DOI=10.1006/jmbi.1996.0185;
RA Mahdi A.A., Sharples G.J., Mandal T.N., Lloyd R.G.;
RT "Holliday junction resolvases encoded by homologous rusA genes in
RT Escherichia coli K-12 and phage 82.";
RL J. Mol. Biol. 257:561-573(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Positively regulate expression of some phage genes. Bacterial
CC host RNA polymerase modified by antitermination proteins transcribes
CC through termination sites that otherwise prevent expression of the
CC regulated genes (By similarity). {ECO:0000250}.
CC -!- MISCELLANEOUS: Encoded by the cryptic lambdoid prophage DLP12.
CC -!- SIMILARITY: Belongs to the phage antitermination Q type 1 family.
CC {ECO:0000305}.
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DR EMBL; X92587; CAA63324.1; -; Genomic_DNA.
DR EMBL; U82598; AAB40747.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73652.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76327.1; -; Genomic_DNA.
DR PIR; S66593; S66593.
DR RefSeq; NP_415083.1; NC_000913.3.
DR RefSeq; WP_001204791.1; NZ_LN832404.1.
DR AlphaFoldDB; Q47274; -.
DR SMR; Q47274; -.
DR BioGRID; 4260894; 131.
DR BioGRID; 849563; 2.
DR IntAct; Q47274; 4.
DR STRING; 511145.b0551; -.
DR PaxDb; Q47274; -.
DR PRIDE; Q47274; -.
DR EnsemblBacteria; AAC73652; AAC73652; b0551.
DR EnsemblBacteria; BAE76327; BAE76327; BAE76327.
DR GeneID; 945177; -.
DR KEGG; ecj:JW0539; -.
DR KEGG; eco:b0551; -.
DR PATRIC; fig|1411691.4.peg.1725; -.
DR EchoBASE; EB3397; -.
DR eggNOG; ENOG502ZQA6; Bacteria.
DR HOGENOM; CLU_129825_0_0_6; -.
DR OMA; CDIQMVL; -.
DR PhylomeDB; Q47274; -.
DR BioCyc; EcoCyc:G6307-MON; -.
DR PRO; PR:Q47274; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IDA:EcoCyc.
DR GO; GO:0060567; P:negative regulation of DNA-templated transcription, termination; IEA:InterPro.
DR GO; GO:0044010; P:single-species biofilm formation; IMP:EcoCyc.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR InterPro; IPR010534; Phage_933W_GpQ.
DR Pfam; PF06530; Phage_antitermQ; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..127
FT /note="Prophage antitermination protein Q homolog QuuD"
FT /id="PRO_0000073891"
SQ SEQUENCE 127 AA; 14176 MW; 78745EF077D6475F CRC64;
MRDIQMVLER WGAWAANNHE DVTWSSIAAG FKGLITSKVK SRPQCCDDDA MIICGCMARL
KKNNSDLHDL LVDYYVVGMT FMSLAGKHCC SDGYIGKRLQ KAEGIIEGML MALDIRLEMD
IVVNNSN
