ID   REQ2_ECOLI              Reviewed;         250 AA.
AC   P76161; P77604;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 2.
DT   03-AUG-2022, entry version 146.
DE   RecName: Full=Prophage antitermination protein Q homolog QuuQ {ECO:0000305};
DE   AltName: Full=Antitermination protein Q homolog from lambdoid prophage Qin;
GN   Name=quuQ; Synonyms=ydfT; OrderedLocusNames=b1559, JW1551;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Positively regulate expression of some phage genes. Bacterial
CC       host RNA polymerase modified by antitermination proteins transcribes
CC       through termination sites that otherwise prevent expression of the
CC       regulated genes (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phage antitermination Q type 2 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00096; AAC74632.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15258.1; -; Genomic_DNA.
DR   PIR; B64911; B64911.
DR   RefSeq; NP_416077.4; NC_000913.3.
DR   RefSeq; WP_001047135.1; NZ_SSUV01000001.1.
DR   AlphaFoldDB; P76161; -.
DR   BioGRID; 4261260; 12.
DR   BioGRID; 850463; 3.
DR   DIP; DIP-28061N; -.
DR   IntAct; P76161; 5.
DR   STRING; 511145.b1559; -.
DR   PaxDb; P76161; -.
DR   PRIDE; P76161; -.
DR   EnsemblBacteria; AAC74632; AAC74632; b1559.
DR   EnsemblBacteria; BAA15258; BAA15258; BAA15258.
DR   GeneID; 66674555; -.
DR   GeneID; 946103; -.
DR   KEGG; ecj:JW1551; -.
DR   KEGG; eco:b1559; -.
DR   PATRIC; fig|1411691.4.peg.704; -.
DR   EchoBASE; EB3593; -.
DR   eggNOG; COG0484; Bacteria.
DR   HOGENOM; CLU_095309_0_0_6; -.
DR   OMA; WEKELCQ; -.
DR   PhylomeDB; P76161; -.
DR   BioCyc; EcoCyc:G6830-MON; -.
DR   PRO; PR:P76161; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.274.110; -; 2.
DR   HAMAP; MF_04158; Antitermination_lambda; 1.
DR   InterPro; IPR038500; Antitermination_sf.
DR   InterPro; IPR003222; Antitermntn.
DR   InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR   Pfam; PF03589; Antiterm; 2.
DR   SUPFAM; SSF57938; SSF57938; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..250
FT                   /note="Prophage antitermination protein Q homolog QuuQ"
FT                   /id="PRO_0000073896"
SQ   SEQUENCE   250 AA;  27926 MW;  275509A4E615F862 CRC64;
     MNLEALPKYY SPKSPKLSDD APATGTGCLT ITDVMAAQGM VQSKAPLGLA LFLAKVGVQD
     PQFAIEGLLN YAMALDNPTL NKLSEEIRLQ IIPYLVSFAF ADYSRSAASK ARCEHCSGTG
     FYNVLREVVK HYRRGESVIK EEWVKELCQH CHGKGEASTA CRGCKGKGIV LDEKRTRFHG
     VPVYKICGRC NGNRFSRLPT TLARRHVQKL VPDLTDYQWY KGYADVIGKL VTKCWQEEAY
     AEAQLRKVTR