RER1C_ARATH
ID RER1C_ARATH Reviewed; 212 AA.
AC Q9ZWI7; O22177;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=Protein RER1C;
DE Short=AtRER1C;
GN Name=RER1C; OrderedLocusNames=At2g23310; ORFNames=T20D16.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10737146; DOI=10.1023/a:1006329828395;
RA Sato K., Ueda T., Nakano A.;
RT "The Arabidopsis thaliana RER1 gene family: its potential role in the
RT endoplasmic reticulum localization of membrane proteins.";
RL Plant Mol. Biol. 41:815-824(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the retrieval of endoplasmic reticulum membrane
CC proteins from the early Golgi compartment. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9ZWI7-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000305}.
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DR EMBL; AB018552; BAA33862.1; -; mRNA.
DR EMBL; AC002391; AAB87102.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC07439.1; -; Genomic_DNA.
DR EMBL; AY069898; AAL47450.1; -; mRNA.
DR EMBL; AY097390; AAM19906.1; -; mRNA.
DR EMBL; AY086455; AAM63458.1; -; mRNA.
DR PIR; T00501; T00501.
DR PIR; T51629; T51629.
DR RefSeq; NP_565550.1; NM_127895.4. [Q9ZWI7-1]
DR AlphaFoldDB; Q9ZWI7; -.
DR BioGRID; 2215; 2.
DR IntAct; Q9ZWI7; 4.
DR STRING; 3702.AT2G23310.1; -.
DR PaxDb; Q9ZWI7; -.
DR EnsemblPlants; AT2G23310.1; AT2G23310.1; AT2G23310. [Q9ZWI7-1]
DR GeneID; 816863; -.
DR Gramene; AT2G23310.1; AT2G23310.1; AT2G23310. [Q9ZWI7-1]
DR KEGG; ath:AT2G23310; -.
DR Araport; AT2G23310; -.
DR TAIR; locus:2058583; AT2G23310.
DR eggNOG; KOG1688; Eukaryota.
DR InParanoid; Q9ZWI7; -.
DR OMA; FACLAFY; -.
DR OrthoDB; 1458086at2759; -.
DR PhylomeDB; Q9ZWI7; -.
DR PRO; PR:Q9ZWI7; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZWI7; baseline and differential.
DR Genevisible; Q9ZWI7; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:GOC.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0006621; P:protein retention in ER lumen; IBA:GO_Central.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR InterPro; IPR004932; Rer1.
DR PANTHER; PTHR10743; PTHR10743; 1.
DR Pfam; PF03248; Rer1; 1.
DR PIRSF; PIRSF016013; AtER_Rer1p; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Alternative splicing; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..212
FT /note="Protein RER1C"
FT /id="PRO_0000207596"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:O48670"
SQ SEQUENCE 212 AA; 24404 MW; C682593141DC515F CRC64;
MESAATAVVP PAAAATTATA TDDNLQSSDS SSPADAVNRL IHAFSQRQQH LLDKTVPHVL
YRWIACLCVV LIYIVRVYFV EGFYIITYAI GIYLLNLIIA FLSPQEDPEA SLTSGGSLPT
RRSDEYRPFV RRLPEFKFWL SIIRAFIIGF MMTFFEVFDV PVFWPILLFY WVMLFFLTMR
KQIQHMIKYR YVPFSFGKKQ YGKKPAPTES SE
