RER1D_ARATH
ID RER1D_ARATH Reviewed; 221 AA.
AC Q9ZPV7; A1A6K2;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein RER1D;
DE Short=AtRER1D;
GN OrderedLocusNames=At2g18240; ORFNames=T30D6.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the retrieval of endoplasmic reticulum membrane
CC proteins from the early Golgi compartment. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9ZPV7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9ZPV7-2; Sequence=VSP_042303;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice
CC site. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000305}.
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DR EMBL; AC006439; AAD15512.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC06743.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06744.1; -; Genomic_DNA.
DR EMBL; AK118500; BAC43104.1; -; mRNA.
DR EMBL; AK228424; BAF00357.1; -; mRNA.
DR EMBL; BT029522; ABL66778.1; -; mRNA.
DR EMBL; BT030063; ABN04801.1; -; mRNA.
DR PIR; A84562; A84562.
DR RefSeq; NP_565431.1; NM_127381.4. [Q9ZPV7-1]
DR RefSeq; NP_849974.1; NM_179643.1. [Q9ZPV7-2]
DR AlphaFoldDB; Q9ZPV7; -.
DR BioGRID; 1696; 4.
DR IntAct; Q9ZPV7; 4.
DR STRING; 3702.AT2G18240.1; -.
DR PaxDb; Q9ZPV7; -.
DR PRIDE; Q9ZPV7; -.
DR ProteomicsDB; 234766; -. [Q9ZPV7-1]
DR EnsemblPlants; AT2G18240.1; AT2G18240.1; AT2G18240. [Q9ZPV7-1]
DR EnsemblPlants; AT2G18240.2; AT2G18240.2; AT2G18240. [Q9ZPV7-2]
DR GeneID; 816339; -.
DR Gramene; AT2G18240.1; AT2G18240.1; AT2G18240. [Q9ZPV7-1]
DR Gramene; AT2G18240.2; AT2G18240.2; AT2G18240. [Q9ZPV7-2]
DR KEGG; ath:AT2G18240; -.
DR Araport; AT2G18240; -.
DR TAIR; locus:2062185; AT2G18240.
DR eggNOG; KOG1688; Eukaryota.
DR HOGENOM; CLU_074889_1_1_1; -.
DR InParanoid; Q9ZPV7; -.
DR OMA; EGDGYTM; -.
DR PhylomeDB; Q9ZPV7; -.
DR PRO; PR:Q9ZPV7; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZPV7; baseline and differential.
DR Genevisible; Q9ZPV7; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:GOC.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0006621; P:protein retention in ER lumen; IBA:GO_Central.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR InterPro; IPR004932; Rer1.
DR PANTHER; PTHR10743; PTHR10743; 1.
DR Pfam; PF03248; Rer1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..221
FT /note="Protein RER1D"
FT /id="PRO_0000415611"
FT TRANSMEM 41..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 200..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 199
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_042303"
SQ SEQUENCE 221 AA; 25730 MW; 16E99577C9617DF7 CRC64;
MEDEPGSENE ADTIVASPLA KWRIEFSKSF QNYLDRSAPN IVRRWLVTLV AAVIYIYRVY
SVYGYFVISY GLATYILNLL IGFLSPKVDP ELEALDPDSL PVDESDEYKP FVRRLPEFKF
WYAATKAFVV AFVMTFFSFL DVPVFWPILL CYWLVLYSLT MKRLIVHMFK YRYFPFDVRK
PVKLLKFLVN SVLTFLRLKK GDGGDDRPSS SNSSQGNEKQ D
