ID   RER1_CAEEL              Reviewed;         191 AA.
AC   P52879;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Protein RER1 homolog;
GN   Name=rer-1; ORFNames=F46C5.8;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: May be involved in protein transport along the secretory
CC       pathway. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000305}.
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DR   EMBL; Z54281; CAA91047.1; -; Genomic_DNA.
DR   PIR; T22302; T22302.
DR   RefSeq; NP_495878.1; NM_063477.6.
DR   AlphaFoldDB; P52879; -.
DR   BioGRID; 39737; 1.
DR   STRING; 6239.F46C5.8.2; -.
DR   EPD; P52879; -.
DR   PaxDb; P52879; -.
DR   EnsemblMetazoa; F46C5.8.1; F46C5.8.1; WBGene00009783.
DR   UCSC; F46C5.8.1; c. elegans.
DR   WormBase; F46C5.8; CE03349; WBGene00009783; rer-1.
DR   eggNOG; KOG1688; Eukaryota.
DR   GeneTree; ENSGT00510000047137; -.
DR   HOGENOM; CLU_074889_1_0_1; -.
DR   InParanoid; P52879; -.
DR   OMA; WYIVAYS; -.
DR   OrthoDB; 1458086at2759; -.
DR   PhylomeDB; P52879; -.
DR   PRO; PR:P52879; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00009783; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:GOC.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0006621; P:protein retention in ER lumen; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR   InterPro; IPR004932; Rer1.
DR   PANTHER; PTHR10743; PTHR10743; 1.
DR   Pfam; PF03248; Rer1; 1.
DR   PIRSF; PIRSF016013; AtER_Rer1p; 1.
PE   3: Inferred from homology;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..191
FT                   /note="Protein RER1 homolog"
FT                   /id="PRO_0000207597"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   191 AA;  22593 MW;  0FB731EF8EF40E80 CRC64;
     MDDGLRDRPG VTSRFFHSLE VKYQYYLDRL TPHTAFRWVI ALISLVFFAS RIILLQGFYI
     VAYAVGIYYL NLFLLFLTPS IDPALEFEDE DDGPVLPSKT NDEFRPFMRR LPEFKFWHSF
     MKATLIAITC TFFEFFDVPV FWPILVMYFF ILTFLTLKRQ IMHMIKYRYI PFTVGKPRMA
     GKEDTGKVVV G