ID   RER1_CHICK              Reviewed;         196 AA.
AC   Q5ZHM5;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Protein RER1;
GN   Name=RER1; ORFNames=RCJMB04_35f13;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Involved in the retrieval of endoplasmic reticulum membrane
CC       proteins from the early Golgi compartment. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ721109; CAG32768.1; -; mRNA.
DR   RefSeq; NP_001006300.1; NM_001006300.1.
DR   RefSeq; XP_015152341.1; XM_015296855.1.
DR   AlphaFoldDB; Q5ZHM5; -.
DR   STRING; 9031.ENSGALP00000039623; -.
DR   PaxDb; Q5ZHM5; -.
DR   Ensembl; ENSGALT00000040422; ENSGALP00000039623; ENSGALG00000021683.
DR   Ensembl; ENSGALT00000051118; ENSGALP00000043636; ENSGALG00000021683.
DR   GeneID; 419397; -.
DR   KEGG; gga:419397; -.
DR   CTD; 11079; -.
DR   VEuPathDB; HostDB:geneid_419397; -.
DR   eggNOG; KOG1688; Eukaryota.
DR   GeneTree; ENSGT00510000047137; -.
DR   HOGENOM; CLU_074889_1_0_1; -.
DR   InParanoid; Q5ZHM5; -.
DR   OMA; WYIVAYS; -.
DR   OrthoDB; 1458086at2759; -.
DR   PhylomeDB; Q5ZHM5; -.
DR   TreeFam; TF300029; -.
DR   PRO; PR:Q5ZHM5; -.
DR   Proteomes; UP000000539; Chromosome 21.
DR   Bgee; ENSGALG00000021683; Expressed in muscle tissue and 14 other tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:GOC.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0006621; P:protein retention in ER lumen; IBA:GO_Central.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR   InterPro; IPR004932; Rer1.
DR   PANTHER; PTHR10743; PTHR10743; 1.
DR   Pfam; PF03248; Rer1; 1.
DR   PIRSF; PIRSF016013; AtER_Rer1p; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..196
FT                   /note="Protein RER1"
FT                   /id="PRO_0000261129"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   196 AA;  23032 MW;  62495F574320B5CB CRC64;
     MSEGDSIGES VHGKPSVVYR FFTRLGQIYQ SWLDKSTPYT AVRWIVTLGL SFIYMIRVYL
     LQGWYIVTYA LGIYHLNLFI AFLSPKVDPS LMEDSDDGPS LPTRQNEEFR PFIRRLPEFK
     FWHSATKGIL VAMACTFFEA FNVPVFWPIL VMYFIMLFCI TMKRQIKHMI KYRYIPFTHG
     KRKYKGKEDV GKTFAS