ID   RER1_DICDI              Reviewed;         188 AA.
AC   Q54D10;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Protein RER1 homolog;
GN   Name=rer1; ORFNames=DDB_G0292588;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May be involved in protein transport along the secretory
CC       pathway. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000194; EAL61097.1; -; Genomic_DNA.
DR   RefSeq; XP_629510.1; XM_629508.1.
DR   AlphaFoldDB; Q54D10; -.
DR   STRING; 44689.DDB0266508; -.
DR   PaxDb; Q54D10; -.
DR   EnsemblProtists; EAL61097; EAL61097; DDB_G0292588.
DR   GeneID; 8628761; -.
DR   KEGG; ddi:DDB_G0292588; -.
DR   dictyBase; DDB_G0292588; rer1.
DR   eggNOG; KOG1688; Eukaryota.
DR   HOGENOM; CLU_074889_0_0_1; -.
DR   InParanoid; Q54D10; -.
DR   OMA; FACLAFY; -.
DR   PhylomeDB; Q54D10; -.
DR   PRO; PR:Q54D10; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:GOC.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0006621; P:protein retention in ER lumen; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR   InterPro; IPR004932; Rer1.
DR   PANTHER; PTHR10743; PTHR10743; 1.
DR   Pfam; PF03248; Rer1; 1.
DR   PIRSF; PIRSF016013; AtER_Rer1p; 1.
PE   3: Inferred from homology;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..188
FT                   /note="Protein RER1 homolog"
FT                   /id="PRO_0000327754"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   188 AA;  22058 MW;  2D4767168E31212D CRC64;
     MPTTIDEGLP APHNFVSFTT LIARKYQNLI EKTISFIPQR WAFVGFLSFL YILRVSLSSG
     GWYVITYALG IFLLTRFIAF LSPKWDPELE EDSGDSLPTT LNRNDDEAKP FIRRLPEFLF
     WHSIFKALFI SIFCTFIPFL DLPVFWPILL LYFIIIFSVT MKKQIKHMIK YKYIPFTVGK
     KTYTKNNS